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B55R1 and B55R2

AJU Pharm Co., Ltd. · FDA-approved active Small molecule

B55R1 and B55R2 are inhibitors of the sodium-glucose cotransporter 2 (SGLT2).

B55R1 and B55R2 are inhibitors of the sodium-glucose cotransporter 2 (SGLT2). Used for Type 2 diabetes, Heart failure.

At a glance

Generic nameB55R1 and B55R2
SponsorAJU Pharm Co., Ltd.
Drug classSGLT2 inhibitor
TargetSGLT2
ModalitySmall molecule
Therapeutic areaDiabetes
PhaseFDA-approved

Mechanism of action

By inhibiting SGLT2, B55R1 and B55R2 reduce glucose reabsorption in the kidneys, thereby lowering blood glucose levels. This action also leads to a mild diuretic effect and a reduction in blood pressure.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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