{"id":"b55r1-and-b55r2","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"10-20%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Hypotension"},{"rate":"null","effect":"Increased urination"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting SGLT2, B55R1 and B55R2 reduce glucose reabsorption in the kidneys, thereby lowering blood glucose levels. This action also leads to a mild diuretic effect and a reduction in blood pressure.","oneSentence":"B55R1 and B55R2 are inhibitors of the sodium-glucose cotransporter 2 (SGLT2).","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:28:02.943Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 2 diabetes"},{"name":"Heart failure"}]},"trialDetails":[{"nctId":"NCT07230184","phase":"PHASE4","title":"To Evaluate the Efficacy and Safety of Combination Therapy With B55R1 and B55R2 Compared to B55R1 Monotherapy in Patients With NPDR","status":"COMPLETED","sponsor":"AJU Pharm Co., Ltd.","startDate":"2022-04-28","conditions":"Non-Proliferative Diabetic Retinopathy","enrollment":52}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"B55R1 and B55R2","genericName":"B55R1 and B55R2","companyName":"AJU Pharm Co., Ltd.","companyId":"aju-pharm-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"B55R1 and B55R2 are inhibitors of the sodium-glucose cotransporter 2 (SGLT2). Used for Type 2 diabetes, Heart failure.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}