Plasmodium heme detoxification pathway — Drug Target

All drugs that target Plasmodium heme detoxification pathway — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

8-aminoquinoline · Antimalarial

Phase 3 pipeline (2)

• Matched-Placebo for Tafenoquine · GlaxoSmithKline · 8-aminoquinoline · Infectious Diseases
  Tafenoquine is an antimalarial drug that works by targeting the parasite's heme detoxification pathway.
• amodiaquine+artesunate/artemether-lumefantrine · University of Ghana Medical School · Antimalarial · Infectious Diseases
  Amodiaquine is a chloroquine derivative that acts as an antimalarial agent by inhibiting the parasite's heme detoxification pathway, while artesunate and artemether-lumefantrine are artemisinin-based combination therapies that rapidly kill the parasite.