8-aminoquinoline

This page covers all 8-aminoquinoline drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting dihydroorotate dehydrogenase, Heme, Plasmodium heme detoxification pathway.

Targets

dihydroorotate dehydrogenase · Heme · Plasmodium heme detoxification pathway

Phase 3 pipeline (3)

• Tafenoquine Oral Tablet · State University of New York - Upstate Medical University · Infectious Diseases
  Tafenoquine is an antimalarial drug that works by targeting the Plasmodium parasite's heme detoxification pathway.
• PQ (0.4) · London School of Hygiene and Tropical Medicine · Infectious Diseases
  PQ (0.4) is an antimalarial drug that works by disrupting the parasite's ability to metabolize heme, leading to its death.
• Matched-Placebo for Tafenoquine · GlaxoSmithKline · Infectious Diseases
  Tafenoquine is an antimalarial drug that works by targeting the parasite's heme detoxification pathway.