Mu-type opioid receptor — Drug Target

All drugs that target Mu-type opioid receptor — marketed and clinical-stage. Includes 11 drug classes acting on this target.

Drug classes

Opioid Antagonist · Opioid Agonist · Atypical Antipsychotic [EPC] · tianeptine · meptazinol · mu-Opioid Receptor Agonist [EPC] · Central Nervous System Stimulant [EPC] · anileridine · Antidiarrheal · dezocine · ciramadol

Marketed (26)

• Relistor · Salix Pharms · Opioid Antagonist · Pain
  Relistor works by blocking opioid receptors in the gut to alleviate constipation.
• Propoxyphene Compound 65 · Opioid Agonist · Pain
• Olinvyk · Trevena · Neuroscience
  Olinvyk works by binding to the mu-type opioid receptor in the brain, which helps to reduce the perception of pain.
• Lybalvi · Alkermes Inc · Atypical Antipsychotic [EPC] · Neuroscience
  Lybalvi blocks the action of opioids at their receptor sites in the brain.
• Movantik · Averitas · Opioid Antagonist · Oncology
  Movantik works by blocking the mu-type opioid receptor, which is responsible for the constipating effects of opioids.
• Symproic · Bdsi · Opioid Antagonist · Metabolic
  Symproic works by blocking the mu-type opioid receptor, which is responsible for slowing down bowel movements.
• Narcan · Adapt · Opioid Antagonist · Neuroscience
• Alfenta · Rising · Opioid Agonist · Pain
• Tilidate · Pain
• Nucynta · Collegium Pharm Inc · Opioid Agonist · Pain
  Nucynta works by binding to opioid receptors in the brain to reduce the perception of pain.
• Sufenta Preservative Free · Rising · Opioid Agonist · Pain
  Sufentanil works by binding to opioid receptors in the brain, spinal cord, and other areas to produce pain relief.
• Bay 4503 · Pain
• Coaxil · Pfizer · tianeptine · Pain
  Tianeptine works by binding to the mu-type opioid receptor, which can affect the brain's response to pain and emotions.
• Tussionex Pennkinetic · Teva · Opioid Agonist · Neuroscience
  Tussionex Pennkinetic works by binding to opioid receptors in the brain, which helps to reduce pain and congestion.
• Duramorph Pf · Pfizer · Opioid Agonist · Neuroscience
  Duramorph Pf works by binding to opioid receptors in the brain and spinal cord, mimicking the natural pain-relieving chemicals in the body.
• Meptamizol · meptazinol · Pain
• Viberzi · AbbVie · mu-Opioid Receptor Agonist [EPC] · Pain
  Viberzi works by activating the mu-opioid receptor in the gut to slow down bowel movements and reduce diarrhea.
• Synalgos-Dc · Caraco · Central Nervous System Stimulant [EPC] · Infectious Disease
• Adopol · anileridine · Pain
• Motofen · Sebela Ireland Ltd · Antidiarrheal · Pain
• Lomotil · Pfizer · Antidiarrheal · Neuroscience
• Movantik · AstraZeneca · Pain
• Adopol · anileridine · Pain
• Dalgan · AstraZeneca · dezocine · Pain
• Meperidine Hydrochloride Preservative Free · Pfizer · Opioid Agonist · Pain
  Meperidine Hydrochloride Preservative Free works by binding to opioid receptors in the brain, altering the perception of and response to pain.
• Opana Er · Endo · Opioid Agonist · Neuroscience

Phase 2 pipeline (1)

• CIRAMADOL · ciramadol · Pain
  CIRAMADOL works by activating the mu-type opioid receptors in the brain, which helps to reduce pain perception.