Glutamate-gated chloride channels — Drug Target

2 drugs 1 marketed 1 in Phase 3

All drugs that target Glutamate-gated chloride channels — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Antiparasitic agent

Marketed (1)

Ivermectin 1% cream · Insel Gruppe AG, University Hospital Bern · Antiparasitic agent · Dermatology
Ivermectin binds to glutamate-gated chloride channels in parasites and arthropods, causing paralysis and death of the organisms.

Phase 3 pipeline (1)

Generic Ivermectin Lotion 0.5% · Actavis Inc. · Antiparasitic agent · Dermatology / Parasitic Infections
Ivermectin binds to glutamate-gated chloride channels in parasitic organisms, causing paralysis and death of the parasite.