DNA polymerase — Drug Target

All drugs that target DNA polymerase — marketed and clinical-stage. Includes 4 drug classes acting on this target.

Drug classes

Antimetabolite · Nucleoside analogue · Nucleoside analog · nucleoside analog

Marketed (1)

• Cytarabine · Nippon Shinyaku Co., Ltd. · Antimetabolite · Oncology
  Cytarabine inhibits DNA polymerase and incorporates into DNA/RNA, killing cells in S-phase.

Phase 3 pipeline (1)

• cidofovir 1% topical ointment · Hospital Universitari Vall d'Hebron Research Institute · Nucleoside analogue · Infectious Diseases
  Cidofovir is an antiviral medication that works by inhibiting viral DNA polymerase.

Phase 2 pipeline (2)

• IBI343,Gemcitabine, Albumin-bound Paclitaxel · Innovent Biologics (Suzhou) Co. Ltd. · Nucleoside analog · Oncology
  Gemcitabine is a nucleoside analog that inhibits DNA synthesis by interfering with DNA polymerase.
• HYML-122; cytarabine · Tarapeutics Science Inc. · nucleoside analog · Oncology
  inhibits DNA polymerase