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cidofovir 1% topical ointment
Cidofovir is an antiviral medication that works by inhibiting viral DNA polymerase.
Cidofovir is an antiviral medication that works by inhibiting viral DNA polymerase. Used for Herpes simplex virus infections, Cytomegalovirus retinitis.
At a glance
| Generic name | cidofovir 1% topical ointment |
|---|---|
| Also known as | Cidofovir |
| Sponsor | Hospital Universitari Vall d'Hebron Research Institute |
| Drug class | Nucleoside analogue |
| Target | DNA polymerase |
| Modality | Small molecule |
| Therapeutic area | Infectious Diseases |
| Phase | Phase 3 |
Mechanism of action
Cidofovir is a nucleoside analogue that is phosphorylated to its active form, which then inhibits viral DNA polymerase, thereby preventing viral replication. This mechanism of action is effective against a wide range of viruses, including herpes simplex virus, cytomegalovirus, and human immunodeficiency virus.
Approved indications
- Herpes simplex virus infections
- Cytomegalovirus retinitis
Common side effects
- Nausea
- Diarrhea
- Vomiting
- Headache
- Fatigue
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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