Androgen receptor — Drug Target
All drugs that target Androgen receptor — marketed and clinical-stage. Includes 26 drug classes acting on this target.
Drug classes
Androgen Receptor Inhibitor [EPC] · oxymetholone · Androgen replacement therapy · oxandrolone · Androgen · Testosterone replacement therapy (TRT) · drostanolone propionate · Androgen receptor inhibitor · androgen · androisoxazole · Androgen [EPC] · Androgenic steroid
Marketed (31)
- Xtandi · Astellas Pharma · Androgen Receptor Inhibitor [EPC] · Oncology
Xtandi works by blocking the androgen receptor, a protein that helps prostate cancer cells grow. - Erleada · Johnson & Johnson · Oncology
Erleada blocks the androgen receptor, a protein that helps cancer cells grow. - Casodex · ANI Pharmaceuticals · Androgen Receptor Inhibitor [EPC] · Oncology
Casodex works by blocking the androgen receptor, a protein that helps prostate cancer cells grow. - Anadrol-50 · Pharmobedient · oxymetholone · Hematology
- topical testosterone gel · Clarus Therapeutics, Inc. · Androgen replacement therapy · Endocrinology
Topical testosterone gel delivers testosterone through the skin to replace deficient hormone levels in hypogonadal men. - NATESTO Testosterone Nasal Gel · Acerus Pharmaceuticals Corporation · Androgen replacement therapy · Endocrinology
NATESTO delivers testosterone through nasal absorption to replace deficient testosterone in hypogonadal men. - Oxandrin · Crealta Pharms Llc · oxandrolone · Bone
- Androgel (Testosterone Gel) · National Institute on Aging (NIA) · Androgen replacement therapy · Endocrinology
Androgel delivers testosterone transdermally to replace deficient testosterone levels in hypogonadal men. - Testosterone Cypionate · Azurity · Androgen · Oncology
- Nilandron · Advanz · Androgen Receptor Inhibitor [EPC] · Oncology
- Androderm® · Allergan · Testosterone replacement therapy (TRT) · Endocrinology
Androderm delivers testosterone transdermally to replace deficient testosterone in hypogonadal men. - Testosterone Product · Bayer · Androgen replacement therapy · Endocrinology
Testosterone replaces or supplements endogenous testosterone to restore normal androgen levels in hypogonadal patients. - Test (T) · The Affiliated Hospital of Qingdao University · Androgen · Endocrinology
Testosterone replacement therapy - testosterone gel (Androgel) · Beersheva Mental Health Center · Androgen replacement therapy · Endocrinology
Testosterone gel replaces deficient endogenous testosterone by transdermal absorption to restore normal androgen levels. - Oxandrin · Par Pharmaceutical, Inc. · Other
- Intrinsa Transdermal testosterone patch · Imperial College Healthcare NHS Trust · Androgen replacement therapy · Endocrinology / Sexual health
Intrinsa delivers testosterone transdermally to restore physiological testosterone levels in women with hypoactive sexual desire disorder. - Metholone · Eli Lilly · drostanolone propionate · Oncology
- Fluotestin · Androgen · Oncology
- Xtandi · Astellas Pharma · Androgen receptor inhibitor · Oncology
Enzalutamide competitively inhibits androgen binding to androgen receptors, blocking nuclear translocation and DNA interaction. - Test Group (B): · Trust Fertility Clinic · androgen · Urology
Testosterone replacement therapy to treat hypogonadism. - Winlevi · Sun Pharma · Androgen Receptor Inhibitor [EPC] · Dermatology
Winlevi works by blocking the androgen receptor, a protein that helps regulate hormones in the body. - Andriol Testocaps · Singapore Clinical Research Institute · Androgen replacement therapy · Endocrinology
Andriol Testocaps delivers testosterone undecanoate in lipid-based capsules to replace deficient testosterone in hypogonadal men. - Testosterone gel 1% · University of Colorado, Denver · Androgen replacement therapy · Endocrinology
Testosterone gel delivers exogenous testosterone through transdermal absorption to replace deficient endogenous testosterone and restore normal androgen levels. - AndroGel 1.62% · Repros Therapeutics Inc. · Androgen replacement therapy · Endocrinology
AndroGel 1.62% is a testosterone replacement therapy that restores physiological testosterone levels in hypogonadal men. - Androxan · androisoxazole · Other
- Testred · Bausch Health · Androgen [EPC] · Oncology
- Androgel · Besins Hlthcare · Androgen [EPC] · Oncology
- Xyosted (Autoinjector) · Endo · Androgen · Oncology
- Aveed · Marius · Androgen · Oncology
Aveed works by binding to androgen receptors in the body, mimicking the effects of natural testosterone. - Testosterone cypionate (200mg/3ml) · Leticia Maria Defendi Barboza Marson · Androgenic steroid · Oncology
- Eulexin · Pfizer Inc. · Androgen Receptor Inhibitor [EPC] · Oncology
Phase 3 pipeline (18)
- Sustanon 250 · Jules Bordet Institute · Anabolic steroid · Endocrinology
Sustanon 250 is an oil-based injectable testosterone blend used to treat low testosterone levels in men. - "Raylis" · The Clinic of Men's Health and Couple Longevity, Russia · Selective androgen receptor modulator (SARM) · Hypogonadism, Muscle wasting diseases
Raylis is a selective androgen receptor modulator (SARM) that acts as a partial agonist to selectively target androgen receptors in muscle and bone, promoting anabolic effects without the side effects associated with full agonists. - Oral testosterone undecanoate, LPCN 1021 · Lipocine Inc. · Androgen replacement therapy · Endocrinology
Oral testosterone undecanoate replaces deficient testosterone by providing exogenous androgen that binds to androgen receptors throughout the body. - Testosterone (T) Gel 1.62% · Abbott · Androgen replacement therapy · Endocrinology
Testosterone gel delivers exogenous testosterone through transdermal absorption to replace deficient endogenous testosterone in hypogonadal men. - TH07 · Triple Hair Inc · Androgen receptor inhibitor · Oncology
TH07 is a small molecule that targets the androgen receptor. - Topical testosterone gel 1.62 % · Lipocine Inc. · androgen replacement therapy · Hormone Replacement Therapy
Topical testosterone gel 1.62% works by delivering testosterone through the skin to increase androgen levels in the body. - Testosterone Gel Wolff · University Hospital Muenster · androgen · Urology
Testosterone gel increases testosterone levels in the body. - Testogel 1% · Laboratoires Besins International · Androgen replacement therapy · Urology
Testogel 1% is a topical testosterone gel used to treat hypogonadism in males. - Long-term course of antiandrogen drugs · The First Affiliated Hospital with Nanjing Medical University · Antiandrogen · Oncology
Antiandrogen drugs block the effects of androgens (male hormones) by inhibiting androgen receptor signaling. - Standard Darolutamide · Jena University Hospital · Nonsteroidal antiandrogen · Oncology
Darolutamide is a nonsteroidal antiandrogen that competitively inhibits the action of androgens, such as testosterone and dihydrotestosterone, at their receptor sites in various tissues. - Axiron Testosterone Topical Solution · Clarus Therapeutics, Inc. · Testosterone replacement therapy (TRT) · Endocrinology
Axiron delivers testosterone transdermally to replace deficient testosterone levels in hypogonadal men. - testosterone pellet (100 mg) · University of Sao Paulo General Hospital · Androgen replacement therapy · Endocrinology
Testosterone pellet delivers sustained testosterone replacement to restore physiological hormone levels in hypogonadal patients. - Androgen Therapy · Alliance for Clinical Trials in Oncology · Androgen replacement therapy · Oncology
Androgen therapy works by supplementing or replacing testosterone and other androgens to restore hormonal balance and promote anabolic effects in patients with androgen deficiency. - testosterone undecanoate alone · Unita Complessa di Ostetricia e Ginecologia · Androgen replacement therapy · Endocrinology
Testosterone undecanoate is an androgen that binds to androgen receptors to replace or supplement testosterone in the body. - Placebo of Darolutamide · Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie · nonsteroidal antiandrogen · Oncology
Darolutamide is a nonsteroidal antiandrogen that competitively inhibits the action of androgens, such as testosterone and dihydrotestosterone, at their receptor sites in various tissues. - LPCN 1021 · Lipocine Inc. · Androgen receptor agonist · Endocrinology
LPCN 1021 is a novel oral androgen receptor agonist designed to deliver testosterone systemically for hormone replacement therapy. - Oral Testosterone Undecanoate · Clarus Therapeutics, Inc. · Androgen replacement therapy · Endocrinology
Oral testosterone undecanoate is a testosterone replacement therapy that restores physiological testosterone levels in hypogonadal men. - Proxalutamide (GT0918) · Suzhou Kintor Pharmaceutical Inc, · Androgen receptor antagonist · Oncology
Proxalutamide is an androgen receptor antagonist.
Phase 2 pipeline (7)
- ARN-509 · Aragon Pharmaceuticals, Inc. · Androgen receptor inhibitor · Oncology
ARN-509 is an androgen receptor inhibitor. - Danazol Once Weekly · Lumara Health, Inc. · Aromatase inhibitor · Oncology
Androgen receptor antagonist - ADT for 9 months and ARTA for 6 months · Tata Memorial Centre · Androgen receptor inhibitor · Oncology
Androgen deprivation therapy (ADT) involves blocking the production of androgens, such as testosterone, which fuel the growth of prostate cancer cells. Androgen receptor signaling inhibitor (ARTA) works by blocking the androgen receptor, preventing cancer cells from receiving the signals they need to grow and multiply. - LPCN 1144 Formulation B · Lipocine Inc. · testosterone replacement therapy · Urology
LPCN 1144 Formulation B is a testosterone replacement therapy. - Brimo PS DDS® · Allergan · Testosterone replacement therapy · Urology
Brimo PS DDS is a testosterone replacement therapy. - ADT for 2 years · Tata Memorial Centre · Anti-androgen · Oncology
Androgen deprivation therapy (ADT) involves the use of medications to suppress the production of androgens, such as testosterone, which can fuel the growth of certain types of cancer. - Bicalutamide Oral Product · Gynaecologisch Oncologisch Centrum Zuid · Nonsteroidal antiandrogen · Oncology
Bicalutamide is a nonsteroidal antiandrogen that inhibits the action of androgens.
Phase 1 pipeline (4)
- ARV-110 in Combination with Abiraterone · Arvinas Androgen Receptor, Inc. · Androgen receptor inhibitor · Oncology
Androgen receptor inhibitor - 2-Hydroxyflutamide · Lidds AB · Anti-androgen · Oncology
Anti-androgen receptor antagonist - AZD8835 in combination with fulvestrant · AstraZeneca · Androgen receptor inhibitor · Oncology
AZD8835 is a selective and potent inhibitor of the androgen receptor. - ARV-110 · Arvinas Inc. · Selective androgen receptor degrader · Oncology
Selective androgen receptor degrader