Last reviewed · How we verify

AZD8835 in combination with fulvestrant

AstraZeneca · Phase 1 active Small molecule

AZD8835 is a selective and potent inhibitor of the androgen receptor.

AZD8835 is a selective and potent inhibitor of the androgen receptor. Used for Hormone receptor-positive breast cancer.

At a glance

Generic nameAZD8835 in combination with fulvestrant
Also known asFaslodex
SponsorAstraZeneca
Drug classAndrogen receptor inhibitor
TargetAndrogen receptor
ModalitySmall molecule
Therapeutic areaOncology
PhasePhase 1

Mechanism of action

AZD8835 works by blocking the androgen receptor, which is a key driver of hormone receptor-positive breast cancer. This leads to a decrease in tumor growth and proliferation.

Approved indications

Common side effects

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