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Lidocaine topical

Ain Shams University · FDA-approved active Small molecule

Lidocaine topical is a Local anesthetic Small molecule drug developed by Ain Shams University. It is currently FDA-approved for Localized pain relief on skin and mucous membranes, Topical anesthesia for minor procedures, Relief of itching and burning sensations. Also known as: lidocaine spray, Lidocaine hydrochloride topical solution, USP, 4%, Anestol pomade(lidocaine), Tramadol hydrochloride.

Lidocaine blocks sodium channels in nerve cell membranes, preventing depolarization and transmission of pain signals.

Lidocaine blocks sodium channels in nerve cell membranes, preventing depolarization and transmission of pain signals. Used for Localized pain relief on skin and mucous membranes, Post-herpetic neuralgia, Minor cuts, burns, and abrasions.

At a glance

Generic nameLidocaine topical
Also known aslidocaine spray, Lidocaine hydrochloride topical solution, USP, 4%, Anestol pomade(lidocaine), Tramadol hydrochloride, Fentanyl citrate
SponsorAin Shams University
Drug classLocal anesthetic
TargetVoltage-gated sodium channels
ModalitySmall molecule
Therapeutic areaPain management / Dermatology
PhaseFDA-approved

Mechanism of action

Lidocaine is a local anesthetic that works by inhibiting sodium influx through voltage-gated sodium channels in nerve fibers. This prevents the generation and propagation of action potentials, thereby blocking pain sensation in the area where it is applied topically. It has a rapid onset and is commonly used for localized pain relief on intact or damaged skin.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Lidocaine topical

What is Lidocaine topical?

Lidocaine topical is a Local anesthetic drug developed by Ain Shams University, indicated for Localized pain relief on skin and mucous membranes, Topical anesthesia for minor procedures, Relief of itching and burning sensations.

How does Lidocaine topical work?

Lidocaine blocks sodium channels in nerve cell membranes, preventing depolarization and transmission of pain signals.

What is Lidocaine topical used for?

Lidocaine topical is indicated for Localized pain relief on skin and mucous membranes, Topical anesthesia for minor procedures, Relief of itching and burning sensations.

Who makes Lidocaine topical?

Lidocaine topical is developed and marketed by Ain Shams University (see full Ain Shams University pipeline at /company/ain-shams-university).

Is Lidocaine topical also known as anything else?

Lidocaine topical is also known as lidocaine spray, Lidocaine hydrochloride topical solution, USP, 4%, Anestol pomade(lidocaine), Tramadol hydrochloride, Fentanyl citrate.

What drug class is Lidocaine topical in?

Lidocaine topical belongs to the Local anesthetic class. See all Local anesthetic drugs at /class/local-anesthetic.

What development phase is Lidocaine topical in?

Lidocaine topical is FDA-approved (marketed).

What are the side effects of Lidocaine topical?

Common side effects of Lidocaine topical include Local skin irritation or erythema, Allergic contact dermatitis, Systemic toxicity (if absorbed in large amounts).

What does Lidocaine topical target?

Lidocaine topical targets Voltage-gated sodium channels and is a Local anesthetic.

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