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Tramadol HCl Contramid® Once A Day
Tramadol HCl Contramid® Once A Day is a Opioid analgesic Small molecule drug developed by Labopharm Inc.. It is currently in Phase 3 development for Moderate to moderately severe pain, Severe pain.
Tramadol HCl is a centrally acting opioid analgesic that works by binding to mu-opioid receptors in the brain.
Tramadol HCl is a centrally acting opioid analgesic that works by binding to mu-opioid receptors in the brain. Used for Moderate to moderately severe pain, Severe pain.
At a glance
| Generic name | Tramadol HCl Contramid® Once A Day |
|---|---|
| Sponsor | Labopharm Inc. |
| Drug class | Opioid analgesic |
| Target | mu-opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Pain management |
| Phase | Phase 3 |
Mechanism of action
This binding action results in the inhibition of pain signal transmission from the brain to the body, providing analgesic effects. Tramadol HCl also has a weak serotonin-norepinephrine reuptake inhibition (SNRI) component, which contributes to its analgesic effects.
Approved indications
- Moderate to moderately severe pain
- Severe pain
Common side effects
- Nausea
- Dizziness
- Headache
- Somnolence
- Constipation
- Vomiting
- Diarrhea
- Fatigue
- Insomnia
- Dry mouth
Key clinical trials
- An Open-Label Long-term Safety Study of Tramadol HCl OAD (Once A Day) 300 mg in the Treatment of Pain Due to Osteoarthritis of the Knee (PHASE3)
- A Comparison of the Analgesic Efficacy and Safety of Once Daily Tramadol HCl / Contramid® Tablets to Twice Daily Tramadol HCl (SR) for the Treatment of Osteoarthritis of the Knee (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Tramadol HCl Contramid® Once A Day CI brief — competitive landscape report
- Tramadol HCl Contramid® Once A Day updates RSS · CI watch RSS
- Labopharm Inc. portfolio CI
Frequently asked questions about Tramadol HCl Contramid® Once A Day
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Who makes Tramadol HCl Contramid® Once A Day?
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Related
- Drug class: All Opioid analgesic drugs
- Target: All drugs targeting mu-opioid receptor
- Manufacturer: Labopharm Inc. — full pipeline
- Therapeutic area: All drugs in Pain management
- Indication: Drugs for Moderate to moderately severe pain
- Indication: Drugs for Severe pain
- Compare: Tramadol HCl Contramid® Once A Day vs similar drugs
- Pricing: Tramadol HCl Contramid® Once A Day cost, discount & access