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Topical analgesic
Topical analgesic is a Topical analgesic Small molecule drug developed by Grünenthal GmbH. It is currently FDA-approved for Localized musculoskeletal pain, Minor arthritis pain, Muscle aches and strains.
Topical analgesics work by delivering pain-relieving agents directly to the skin and underlying tissues to reduce localized pain sensation.
Topical analgesics work by delivering pain-relieving agents directly to the skin and underlying tissues to reduce localized pain sensation. Used for Localized musculoskeletal pain, Minor arthritis pain, Muscle aches and strains.
At a glance
| Generic name | Topical analgesic |
|---|---|
| Sponsor | Grünenthal GmbH |
| Drug class | Topical analgesic |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | FDA-approved |
Mechanism of action
Topical analgesics function through various mechanisms depending on their active ingredients—commonly including local anesthetics (which block nerve conduction), NSAIDs (which reduce inflammation and prostaglandin production), or counterirritants (which create a competing sensation). By applying these agents directly to the affected area, they achieve localized pain relief with minimal systemic absorption and side effects.
Approved indications
- Localized musculoskeletal pain
- Minor arthritis pain
- Muscle aches and strains
Common side effects
- Skin irritation or redness
- Allergic contact dermatitis
- Burning or stinging at application site
Key clinical trials
- Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) (PHASE2)
- The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster (NA)
- Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery (PHASE4)
- A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015) (PHASE3)
- Sunitinib or Cediranib for Alveolar Soft Part Sarcoma (PHASE2)
- The Analgesic Efficacy and Safety of Loxoprofen Sodium Patch in Patients With Herpes Zoster (NA)
- The Analgesic Efficacy and Safety of Flurbiprofen Patch in Patients With Herpes Zoster (NA)
- Evaluation of the Analgesic Effect of Ropivacaine in Topical Use at the Thin Skin Graft Donor Site (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Topical analgesic CI brief — competitive landscape report
- Topical analgesic updates RSS · CI watch RSS
- Grünenthal GmbH portfolio CI
Frequently asked questions about Topical analgesic
What is Topical analgesic?
How does Topical analgesic work?
What is Topical analgesic used for?
Who makes Topical analgesic?
What drug class is Topical analgesic in?
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What are the side effects of Topical analgesic?
Related
- Drug class: All Topical analgesic drugs
- Manufacturer: Grünenthal GmbH — full pipeline
- Therapeutic area: All drugs in Pain Management
- Indication: Drugs for Localized musculoskeletal pain
- Indication: Drugs for Minor arthritis pain
- Indication: Drugs for Muscle aches and strains
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing