Topical analgesic

This page covers all Topical analgesic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting TRPV1, Neutral endopeptidase (NEP).

Targets

TRPV1 · Neutral endopeptidase (NEP)

Marketed (3)

• Pain Relief Ointment · Johnson & Johnson Consumer and Personal Products Worldwide · Pain Management
  Pain Relief Ointment provides topical analgesia by delivering active ingredients through the skin to reduce localized pain and inflammation.
• Relief Pro cream · Bayer · Pain Management
  Relief Pro cream provides topical pain relief through a combination of active ingredients that reduce inflammation and numb localized pain.
• Topical analgesic · Grünenthal GmbH · Pain Management
  Topical analgesics work by delivering pain-relieving agents directly to the skin and underlying tissues to reduce localized pain sensation.

Phase 3 pipeline (1)

• NGX-4010, 8% capsaicin patch · NeurogesX · Pain management
  NGX-4010, an 8% capsaicin patch, works by activating TRPV1 receptors to reduce pain.

Phase 2 pipeline (4)

• Capsaicin, USP 0.0375% · Express Specialty Pharmacy · Pain Management
  Activates TRPV1 receptors
• Capsaicin 0.1% Cream · Henry Ford Health System · Dermatology
  Activates TRPV1 receptors to reduce pain
• Capsaicin 1% oral solution · Georg Kägi, MD · Pain management
  Capsaicin activates TRPV1 receptors, leading to the release of substance P and subsequent pain relief.
• EpiCept-NP-1 Cream · EpiCept Corporation · Pain management
  EpiCept-NP-1 Cream is a topical analgesic that works by blocking the production of substance P, a neuropeptide involved in pain transmission.