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Promescent Lidocaine Spray
Promescent Lidocaine Spray is a Topical local anesthetic Small molecule drug developed by Eugene Y Rhee, MD. It is currently in Phase 3 development for Premature ejaculation.
Lidocaine spray topically anesthetizes nerve endings in penile tissue to reduce sensory stimulation and delay ejaculation.
Lidocaine spray topically anesthetizes nerve endings in penile tissue to reduce sensory stimulation and delay ejaculation. Used for Premature ejaculation.
At a glance
| Generic name | Promescent Lidocaine Spray |
|---|---|
| Sponsor | Eugene Y Rhee, MD |
| Drug class | Topical local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Urology / Sexual Health |
| Phase | Phase 3 |
Mechanism of action
Lidocaine is a local anesthetic that blocks sodium channels in nerve fibers, reducing the conduction of pain and sensory signals. When applied topically to the penis, it decreases penile sensitivity, thereby prolonging the time to ejaculation and improving control during sexual activity. This mechanism addresses premature ejaculation by desensitizing the tissue without systemic absorption.
Approved indications
- Premature ejaculation
Common side effects
- Penile numbness or reduced sensation
- Local irritation or erythema
- Temporary loss of erectile function
- Partner genital numbness (from transfer)
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Promescent Lidocaine Spray CI brief — competitive landscape report
- Promescent Lidocaine Spray updates RSS · CI watch RSS
- Eugene Y Rhee, MD portfolio CI
Frequently asked questions about Promescent Lidocaine Spray
What is Promescent Lidocaine Spray?
How does Promescent Lidocaine Spray work?
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Who makes Promescent Lidocaine Spray?
What drug class is Promescent Lidocaine Spray in?
What development phase is Promescent Lidocaine Spray in?
What are the side effects of Promescent Lidocaine Spray?
What does Promescent Lidocaine Spray target?
Related
- Drug class: All Topical local anesthetic drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Eugene Y Rhee, MD — full pipeline
- Therapeutic area: All drugs in Urology / Sexual Health
- Indication: Drugs for Premature ejaculation