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PL nasal spray
PL nasal spray is a Corticosteroid Small molecule drug developed by University of Chicago. It is currently FDA-approved for Allergic rhinitis, Nasal congestion, Sinus pressure.
PL nasal spray is a corticosteroid used to reduce inflammation in the nasal passages.
PL nasal spray is a corticosteroid used to reduce inflammation in the nasal passages. Used for Allergic rhinitis, Nasal congestion, Sinus pressure.
At a glance
| Generic name | PL nasal spray |
|---|---|
| Sponsor | University of Chicago |
| Drug class | Corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Respiratory |
| Phase | FDA-approved |
Mechanism of action
PL nasal spray works by decreasing the production of inflammatory chemicals in the nasal mucosa, thereby reducing swelling and congestion. This is achieved through the action of the corticosteroid on the glucocorticoid receptor, which regulates the expression of genes involved in inflammation. By reducing inflammation, PL nasal spray helps to alleviate symptoms of nasal congestion, runny nose, and sinus pressure associated with allergic rhinitis and other conditions.
Approved indications
- Allergic rhinitis
- Nasal congestion
- Sinus pressure
Common side effects
- Nasal irritation
- Headache
- Nausea
Key clinical trials
- Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors (PHASE2)
- Modulating Socially Adaptive Mirror System Functioning in Autism by Oxytocin (PHASE3)
- Oxytocin and Interpersonal Motor Resonance (PHASE4)
- Effect of Veramyst and Olopatadine 0.2% Opthalmic Solution on Allergy Symptoms (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- PL nasal spray CI brief — competitive landscape report
- PL nasal spray updates RSS · CI watch RSS
- University of Chicago portfolio CI
Frequently asked questions about PL nasal spray
What is PL nasal spray?
How does PL nasal spray work?
What is PL nasal spray used for?
Who makes PL nasal spray?
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Related
- Drug class: All Corticosteroid drugs
- Target: All drugs targeting Glucocorticoid receptor
- Manufacturer: University of Chicago — full pipeline
- Therapeutic area: All drugs in Respiratory
- Indication: Drugs for Allergic rhinitis
- Indication: Drugs for Nasal congestion
- Indication: Drugs for Sinus pressure
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing