NCT03010670 is a Phase 4 clinical trial of Oxytocin in Social Behavior, sponsored by KU Leuven.

Who is sponsoring NCT03010670?

NCT03010670 is sponsored by KU Leuven.

What drugs are being tested in NCT03010670?

Interventions in NCT03010670: Oxytocin, Placebo.

What condition does NCT03010670 study?

NCT03010670 studies Social Behavior.

Is NCT03010670 still recruiting?

NCT03010670 is currently completed. Last updated 3 January 2017.

Last reviewed 2017-01-03 · How we verify

NCT03010670

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Oxytocin-based Pharmacotherapy: Investigating the Effect on Interpersonal Motor Resonance Upon Direct Eye Gaze

Completed Phase 4 Last updated 3 January 2017

What this trial tests

Phase 4 trial testing Oxytocin in Social Behavior in 27 participants. Completed in 1 December 2016.

Timeline

1 January 2016

Primary endpoint
1 August 2016

1 December 2016

Quick facts

Lead sponsor	KU Leuven
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	basic science
Enrollment	27
Start date	1 January 2016
Primary completion	1 August 2016
Estimated completion	1 December 2016
Sites	1 location across Belgium

Drugs / interventions tested

Oxytocin (OXYTOCIN) — full drug profile →
Placebo

Conditions studied

Social Behavior — all drugs for Social Behavior →

Sponsor

KU Leuven — full company profile →

Who can join

Adults 18 to 35, male only, with Social Behavior. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Assessment of interpersonal motor resonance (IMR)
Time frame: 30 minutes
TMS will be applied to assess IMR during different observational conditions after a single dose of nasal spray

Sponsor's own description

Among different social cues from the environment, the eyes constitute a very salient source for initiating social interaction or communication. Interestingly, previous work from our (Prinsen et al., 2016) and other labs demonstrated that direct eye contact between two individuals can readily evoke an increased propensity to 'mirror' other peoples' actions. Particularly, using transcranial magnetic stimulation (TMS), the investigators showed that mirror-motor mapping at the level of the primary motor cortex (M1), also known as "interpersonal motor resonance" (IMR), is significantly increased upon the observation of actions accompanied by direct eye contact, compared to the observation of actions accompanied by averted eye gaze. With the present study, the investigators aim to investigate the role of eye contact on IMR further, and in particular, explore whether administration of the 'prosocial' neuropeptide oxytocin (OT) can influence eye-contact induced IMR. In general, OT is known to play an important role in promoting prosocial behavior and the perception of socially-relevant stimuli, such as eye gaze. To date however, the link between OT and IMR is less clear.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Oxytocin

Trials testing the same drug.

NCT07401524 — Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage · Phase 4 · not yet recruiting
NCT07188207 — Rectal Misoprostol for Reducing Blood Loss in Elective Cesarean Section · NA · not yet recruiting
NCT06968481 — Sublingual Oxytocin for the Prevention of Post-partum Hemorrhage · Phase 2 · not yet recruiting
NCT07265180 — Oxytocin-Augmented Group Psychotherapy for Patients With Schizophrenia - an Oxytocin-dose Comparison · NA · recruiting
NCT07119398 — Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM · Phase 4 · recruiting

Other recruiting trials for Social Behavior

Currently open trials in the same condition.

NCT07191782 — Examining the Efficacy of the PRAISE With Coaching Program · NA · recruiting
NCT06835205 — Prevention Workshop to Address Bullying Behaviors in Schools · NA · active not recruiting
NCT06152211 — Music-Based Interventions, Aging, Alzheimer's Disease · NA · recruiting
NCT06675526 — Detour: a Smartphone Game to Help Youth Quit Smoking · NA · recruiting

Other KU Leuven trials

Trials by the same sponsor.

NCT07508696 — Cerebellar Research in Ultrasound Stimulation · NA · not yet recruiting
NCT07476716 — Peer-modeled Intervention · NA · not yet recruiting
NCT07534384 — Automated CPET Interpretation: International Validation Study · not yet recruiting
NCT07419555 — Belgian Lung Function Study · recruiting
NCT07295600 — Postprandial Effect of Isocaloric Challenge Meals Enriched With Indigenous Fruits and Vegetables on Glucose Metabolism i · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03010670 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by KU Leuven
Last refreshed: 3 January 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03010670.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing