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PCA with Chlorhydrate of Morphine
PCA with Chlorhydrate of Morphine is a Opioid analgesic Small molecule drug developed by Centre Hospitalier Universitaire de Besancon. It is currently in Phase 3 development for Acute postoperative pain, Acute pain management in hospitalized patients. Also known as: Patient Controlled Analgesia (PCA).
Morphine hydrochloride delivered via patient-controlled analgesia (PCA) allows patients to self-administer opioid doses on demand for pain relief.
Morphine hydrochloride delivered via patient-controlled analgesia (PCA) allows patients to self-administer opioid doses on demand for pain relief. Used for Acute postoperative pain, Acute pain management in hospitalized patients.
At a glance
| Generic name | PCA with Chlorhydrate of Morphine |
|---|---|
| Also known as | Patient Controlled Analgesia (PCA) |
| Sponsor | Centre Hospitalier Universitaire de Besancon |
| Drug class | Opioid analgesic |
| Target | Mu-opioid receptor (μ-OR) |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | Phase 3 |
Mechanism of action
Morphine is a mu-opioid receptor agonist that binds to opioid receptors in the central and peripheral nervous system to reduce pain perception and emotional response to pain. PCA is a delivery system that enables patients to control the timing and frequency of their analgesic doses within preset safety limits, improving pain management and patient satisfaction. This formulation is typically used in acute postoperative or acute pain settings.
Approved indications
- Acute postoperative pain
- Acute pain management in hospitalized patients
Common side effects
- Nausea and vomiting
- Drowsiness/sedation
- Constipation
- Pruritus
- Respiratory depression
- Hypotension
Key clinical trials
- Efficacy of the Ultrasound-guided Transversus Abdominis Plane Block in Open Aortic Abdominal Aneurysm Repair Surgery (PHASE3)
- Association Between Clinical Effect of Morphine With PCA After Surgery and Pharmacogenetics
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- PCA with Chlorhydrate of Morphine CI brief — competitive landscape report
- PCA with Chlorhydrate of Morphine updates RSS · CI watch RSS
- Centre Hospitalier Universitaire de Besancon portfolio CI
Frequently asked questions about PCA with Chlorhydrate of Morphine
What is PCA with Chlorhydrate of Morphine?
How does PCA with Chlorhydrate of Morphine work?
What is PCA with Chlorhydrate of Morphine used for?
Who makes PCA with Chlorhydrate of Morphine?
Is PCA with Chlorhydrate of Morphine also known as anything else?
What drug class is PCA with Chlorhydrate of Morphine in?
What development phase is PCA with Chlorhydrate of Morphine in?
What are the side effects of PCA with Chlorhydrate of Morphine?
What does PCA with Chlorhydrate of Morphine target?
Related
- Drug class: All Opioid analgesic drugs
- Target: All drugs targeting Mu-opioid receptor (μ-OR)
- Manufacturer: Centre Hospitalier Universitaire de Besancon — full pipeline
- Therapeutic area: All drugs in Pain Management
- Indication: Drugs for Acute postoperative pain
- Indication: Drugs for Acute pain management in hospitalized patients
- Also known as: Patient Controlled Analgesia (PCA)