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lidocaine pretreatment

Benaroya Research Institute · FDA-approved active Small molecule

lidocaine pretreatment is a Local anesthetic Small molecule drug developed by Benaroya Research Institute. It is currently FDA-approved for Pretreatment to reduce pain and adverse reactions during immunotherapy or vaccine administration.

Lidocaine pretreatment reduces pain and adverse reactions during subsequent injections or procedures by blocking sodium channels and numbing the injection site.

Lidocaine pretreatment reduces pain and adverse reactions during subsequent injections or procedures by blocking sodium channels and numbing the injection site. Used for Pretreatment to reduce pain and adverse reactions during immunotherapy or vaccine administration.

At a glance

Generic namelidocaine pretreatment
SponsorBenaroya Research Institute
Drug classLocal anesthetic
TargetVoltage-gated sodium channels
ModalitySmall molecule
Therapeutic areaPain management / Anesthesia
PhaseFDA-approved

Mechanism of action

Lidocaine is a local anesthetic that works by blocking voltage-gated sodium channels in nerve fibers, preventing the generation and propagation of action potentials. When administered as a pretreatment before another injection or procedure, it anesthetizes the target tissue, reducing pain perception and potentially mitigating systemic reactions to the subsequent intervention.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about lidocaine pretreatment

What is lidocaine pretreatment?

lidocaine pretreatment is a Local anesthetic drug developed by Benaroya Research Institute, indicated for Pretreatment to reduce pain and adverse reactions during immunotherapy or vaccine administration.

How does lidocaine pretreatment work?

Lidocaine pretreatment reduces pain and adverse reactions during subsequent injections or procedures by blocking sodium channels and numbing the injection site.

What is lidocaine pretreatment used for?

lidocaine pretreatment is indicated for Pretreatment to reduce pain and adverse reactions during immunotherapy or vaccine administration.

Who makes lidocaine pretreatment?

lidocaine pretreatment is developed and marketed by Benaroya Research Institute (see full Benaroya Research Institute pipeline at /company/benaroya-research-institute).

What drug class is lidocaine pretreatment in?

lidocaine pretreatment belongs to the Local anesthetic class. See all Local anesthetic drugs at /class/local-anesthetic.

What development phase is lidocaine pretreatment in?

lidocaine pretreatment is FDA-approved (marketed).

What are the side effects of lidocaine pretreatment?

Common side effects of lidocaine pretreatment include Local erythema or swelling at injection site, Transient numbness, Allergic reaction (rare).

What does lidocaine pretreatment target?

lidocaine pretreatment targets Voltage-gated sodium channels and is a Local anesthetic.

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