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Femoral Nerve Block Bupivacaine
Femoral Nerve Block Bupivacaine is a Local anesthetic Small molecule drug developed by The New England Baptist Hospital. It is currently in Phase 3 development for Regional anesthesia for femoral nerve block in surgical procedures, Postoperative pain management in lower extremity surgery. Also known as: Bupivacaine.
Bupivacaine blocks sodium channels in nerve fibers, preventing the generation and propagation of action potentials to produce local anesthesia in the femoral nerve distribution.
Bupivacaine blocks sodium channels in nerve fibers, preventing the generation and propagation of action potentials to produce local anesthesia in the femoral nerve distribution. Used for Regional anesthesia for femoral nerve block in surgical procedures, Postoperative pain management in lower extremity surgery.
At a glance
| Generic name | Femoral Nerve Block Bupivacaine |
|---|---|
| Also known as | Bupivacaine |
| Sponsor | The New England Baptist Hospital |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia / Pain Management |
| Phase | Phase 3 |
Mechanism of action
Bupivacaine is a long-acting local anesthetic that reversibly inhibits sodium influx through voltage-gated sodium channels in nerve cell membranes. When administered as a femoral nerve block, it diffuses into nearby nerve tissue and prevents depolarization, thereby blocking sensory and motor nerve conduction in the femoral nerve territory. This produces regional anesthesia and analgesia for surgical procedures and pain management in the lower extremity.
Approved indications
- Regional anesthesia for femoral nerve block in surgical procedures
- Postoperative pain management in lower extremity surgery
Common side effects
- Systemic toxicity (CNS effects: tremor, seizure)
- Cardiovascular effects (hypotension, arrhythmia)
- Local tissue irritation or hematoma at injection site
- Nerve injury or paresthesia
Key clinical trials
- Comparison of Femoral Nerve Block and Combined PENG Plus Femoral Nerve Block in Geriatric Hip Surgery (NA)
- Genicular Nerve Block Added to Femoral Nerve Block for Analgesia After Total Knee Arthroplasty (NA)
- Comparison of Pericapsular Nerve Group+ Lateral Femoral Cutaneous Nerve Block Versus Lumbar Erector Spinae Plane Block in Hip Arthroplasty Surgery
- Peripheral Nerve Blocks and Postoperative Pain and Mobilization After Total Knee Arthroplasty
- Ultrasound Guided Femoral Nerve Block (NA)
- Sacral ESPB vs. PENG Block for Hip Hemiarthroplasty Analgesia (NA)
- Pericapsular Nerve Group Block Added to Intra-articular Corticosteroid Injection in the Treatment of Hip Pain
- Comparison Between Combined Biceps Femoris Short Head Block and Adductor Canal Block Versus Genicular Nerve Block (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Femoral Nerve Block Bupivacaine CI brief — competitive landscape report
- Femoral Nerve Block Bupivacaine updates RSS · CI watch RSS
- The New England Baptist Hospital portfolio CI
Frequently asked questions about Femoral Nerve Block Bupivacaine
What is Femoral Nerve Block Bupivacaine?
How does Femoral Nerve Block Bupivacaine work?
What is Femoral Nerve Block Bupivacaine used for?
Who makes Femoral Nerve Block Bupivacaine?
Is Femoral Nerve Block Bupivacaine also known as anything else?
What drug class is Femoral Nerve Block Bupivacaine in?
What development phase is Femoral Nerve Block Bupivacaine in?
What are the side effects of Femoral Nerve Block Bupivacaine?
What does Femoral Nerve Block Bupivacaine target?
Related
- Drug class: All Local anesthetic drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: The New England Baptist Hospital — full pipeline
- Therapeutic area: All drugs in Anesthesia / Pain Management
- Indication: Drugs for Regional anesthesia for femoral nerve block in surgical procedures
- Indication: Drugs for Postoperative pain management in lower extremity surgery
- Also known as: Bupivacaine
- Compare: Femoral Nerve Block Bupivacaine vs similar drugs
- Pricing: Femoral Nerve Block Bupivacaine cost, discount & access