Last reviewed · How we verify
NCT07445009
Comparison of Pericapsular Nerve Group+ Lateral Femoral Cutaneous Nerve Block Versus Lumbar Erector Spinae Plane Block in Hip Arthroplasty Surgery
trial testing PENG + LFCN Block in Hip Arthroplasty in 62 participants. Completed in 1 October 2025.
1 September 2025
Quick facts
| Lead sponsor | Fatih Sultan Mehmet Training and Research Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 62 |
| Start date | 1 July 2024 |
| Primary completion | 1 September 2025 |
| Estimated completion | 1 October 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- PENG + LFCN Block
- PENG + Lumbar ESP Block
Conditions studied
- Hip Arthroplasty — all drugs for Hip Arthroplasty →
- Postoperative Pain — all drugs for Postoperative Pain →
- Hip Fractures — all drugs for Hip Fractures →
- Postoperative Delirium (POD) — all drugs for Postoperative Delirium (POD) →
Sponsor
Fatih Sultan Mehmet Training and Research Hospital
Who can join
65 and older, any sex, with Hip Arthroplasty or Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hip replacement surgery (partial or total hip arthroplasty) is commonly performed in elderly patients and is associated with significant postoperative pain. Effective pain management is critical to support early mobilization, reduce complications, shorten hospital stay, and prevent postoperative delirium.This observational study evaluates the effect of two ultrasound-guided regional analgesia approaches on postoperative pain and recovery quality in patients aged 65 years and older undergoing hip arthroplasty under general anesthesia: Group 1: Pericapsular Nerve Group (PENG) block + Lateral Femoral Cutaneous Nerve (LFCN) block Group 2: PENG block + Lumbar Erector Spinae Plane (ESP) block Both techniques are applied as part of routine clinical practice at our institution. The primary outcome is quality of recovery assessed by the QoR-15 questionnaire at 24 hours after surgery. Secondary outcomes include postoperative opioid consumption, pain scores (NRS), incidence of postoperative delirium (NU-DESC), nausea and vomiting, and time to mobilization. Patients are also followed up by telephone at postoperative day 7 and day 30 for mortality and morbidity assessment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07445009
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hip Arthroplasty
Currently open trials in the same condition.
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- NCT07442721 — Sacral ESPB vs. PENG Block for Hip Hemiarthroplasty Analgesia · NA · recruiting
- NCT07212699 — Development of an Outcome Score for Patients With Knee Osteoarthritis and Knee Joint Endoprosthesis Using an App · NA · recruiting
- NCT07017192 — OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study · NA · recruiting
Other Fatih Sultan Mehmet Training and Research Hospital trials
Trials by the same sponsor.
- NCT07589582 — Active Noise-Cancelling Headphones Reduce Operative Time and Improve Procedural Consistency in ACL Reconstruction l · NA · active not recruiting
- NCT07523828 — Laryngeal Edema Assessment by Cuff Leak Test and Ultrasound in ICU Patients and Its Relationship With Weaning Success · not yet recruiting
- NCT07487038 — The Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis · not yet recruiting
- NCT07485465 — Lymphoedema Diagnosis and Treatment · not yet recruiting
- NCT07451925 — Prediction of Postoperative Pain Using Venous Cannulation Pain and Preoperative Anxiety Scores · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07445009 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fatih Sultan Mehmet Training and Research Hospital
- Last refreshed: 6 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07445009.
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