Last reviewed · How we verify
Ex- vivo cultured adult allogeneic MSCs
Ex- vivo cultured adult allogeneic MSCs is a Cell therapy Biologic drug developed by Stempeutics Research Pvt Ltd. It is currently in Phase 2 development for Osteoarthritis, Bone nonunion.
Ex- vivo cultured adult allogeneic MSCs are thought to exert their therapeutic effects through paracrine mechanisms, releasing various growth factors and cytokines that promote tissue repair and regeneration.
Ex- vivo cultured adult allogeneic MSCs are thought to exert their therapeutic effects through paracrine mechanisms, releasing various growth factors and cytokines that promote tissue repair and regeneration. Used for Osteoarthritis, Bone nonunion.
At a glance
| Generic name | Ex- vivo cultured adult allogeneic MSCs |
|---|---|
| Sponsor | Stempeutics Research Pvt Ltd |
| Drug class | Cell therapy |
| Modality | Biologic |
| Therapeutic area | Regenerative medicine, Orthopedics |
| Phase | Phase 2 |
Mechanism of action
The exact molecular targets of MSCs are not fully understood, but they are believed to interact with various cell surface receptors and signaling pathways to modulate immune responses, reduce inflammation, and promote angiogenesis. This leads to improved tissue repair and regeneration in various disease states.
Approved indications
- Osteoarthritis
- Bone nonunion
Common side effects
- Infusion-related reactions
- Infection
- Tumor progression
Key clinical trials
- Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Buerger's Disease (PHASE4)
- Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD) (PHASE2)
- Allogeneic Mesenchymal Stem Cells in Osteoarthritis (PHASE2)
- Allogeneic Mesenchymal Stem Cells for Osteoarthritis (PHASE2)
- Ex Vivo Cultured Adult Allogenic MSCs in Ischemic Cerebral Stroke (PHASE1, PHASE2)
- Ex Vivo Cultured Bone Marrow Derived Allogenic MSCs in AMI (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Ex- vivo cultured adult allogeneic MSCs CI brief — competitive landscape report
- Ex- vivo cultured adult allogeneic MSCs updates RSS · CI watch RSS
- Stempeutics Research Pvt Ltd portfolio CI
Frequently asked questions about Ex- vivo cultured adult allogeneic MSCs
What is Ex- vivo cultured adult allogeneic MSCs?
How does Ex- vivo cultured adult allogeneic MSCs work?
What is Ex- vivo cultured adult allogeneic MSCs used for?
Who makes Ex- vivo cultured adult allogeneic MSCs?
What drug class is Ex- vivo cultured adult allogeneic MSCs in?
What development phase is Ex- vivo cultured adult allogeneic MSCs in?
What are the side effects of Ex- vivo cultured adult allogeneic MSCs?
Related
- Drug class: All Cell therapy drugs
- Manufacturer: Stempeutics Research Pvt Ltd — full pipeline
- Therapeutic area: All drugs in Regenerative medicine, Orthopedics
- Indication: Drugs for Osteoarthritis
- Indication: Drugs for Bone nonunion
- Compare: Ex- vivo cultured adult allogeneic MSCs vs similar drugs
- Pricing: Ex- vivo cultured adult allogeneic MSCs cost, discount & access