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Epidural analgesia:Levobupivacaine0,125%
Epidural analgesia:Levobupivacaine0,125% is a Local anesthetic (amide class) Small molecule drug developed by Hospital General Universitario Elche. It is currently in Phase 3 development for Epidural anesthesia and analgesia for surgical procedures, Epidural analgesia for labor and delivery, Postoperative pain management via epidural administration. Also known as: Epidural analgesia.
Levobupivacaine is a local anesthetic that blocks sodium channels in nerve fibers, preventing the generation and propagation of action potentials to produce regional anesthesia.
Levobupivacaine is a local anesthetic that blocks sodium channels in nerve fibers, preventing the generation and propagation of action potentials to produce regional anesthesia. Used for Epidural anesthesia and analgesia for surgical procedures, Epidural analgesia for labor and delivery, Postoperative pain management via epidural administration.
At a glance
| Generic name | Epidural analgesia:Levobupivacaine0,125% |
|---|---|
| Also known as | Epidural analgesia |
| Sponsor | Hospital General Universitario Elche |
| Drug class | Local anesthetic (amide class) |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia/Pain Management |
| Phase | Phase 3 |
Mechanism of action
Levobupivacaine is the S-enantiomer of bupivacaine, a long-acting amide local anesthetic. It reversibly binds to and blocks voltage-gated sodium channels on the inner surface of nerve cell membranes, preventing depolarization and nerve impulse transmission. When administered epidurally, it produces anesthesia and analgesia in the lower body by blocking sensory and motor nerves in the epidural space.
Approved indications
- Epidural anesthesia and analgesia for surgical procedures
- Epidural analgesia for labor and delivery
- Postoperative pain management via epidural administration
Common side effects
- Hypotension
- Bradycardia
- Headache
- Nausea
- Urinary retention
- Pruritus
- Neurological toxicity (at high doses)
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Epidural analgesia:Levobupivacaine0,125% CI brief — competitive landscape report
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- Hospital General Universitario Elche portfolio CI
Frequently asked questions about Epidural analgesia:Levobupivacaine0,125%
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Related
- Drug class: All Local anesthetic (amide class) drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Hospital General Universitario Elche — full pipeline
- Therapeutic area: All drugs in Anesthesia/Pain Management
- Indication: Drugs for Epidural anesthesia and analgesia for surgical procedures
- Indication: Drugs for Epidural analgesia for labor and delivery
- Indication: Drugs for Postoperative pain management via epidural administration
- Also known as: Epidural analgesia
- Compare: Epidural analgesia:Levobupivacaine0,125% vs similar drugs
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