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Elexacaftor-tezacaftor-ivacaftor exposure
Elexacaftor-tezacaftor-ivacaftor exposure is a CFTR potentiator Small molecule drug developed by Jennifer Taylor-Cousar. It is currently in Phase 2 development for Cystic fibrosis.
CFTR potentiator
CFTR potentiator Used for Cystic fibrosis.
At a glance
| Generic name | Elexacaftor-tezacaftor-ivacaftor exposure |
|---|---|
| Sponsor | Jennifer Taylor-Cousar |
| Drug class | CFTR potentiator |
| Target | CFTR |
| Modality | Small molecule |
| Therapeutic area | Respiratory |
| Phase | Phase 2 |
Mechanism of action
Elexacaftor, tezacaftor, and ivacaftor work together to increase the amount of functional CFTR protein at the cell surface, leading to improved chloride transport and mucociliary clearance.
Approved indications
- Cystic fibrosis
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Headache
- Fatigue
Key clinical trials
- CFTR Modulators in Pregnancy and Postpartum
- Impact of Triple Combination CFTR Therapy on Sinus Disease.
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Elexacaftor-tezacaftor-ivacaftor exposure CI brief — competitive landscape report
- Elexacaftor-tezacaftor-ivacaftor exposure updates RSS · CI watch RSS
- Jennifer Taylor-Cousar portfolio CI
Frequently asked questions about Elexacaftor-tezacaftor-ivacaftor exposure
What is Elexacaftor-tezacaftor-ivacaftor exposure?
How does Elexacaftor-tezacaftor-ivacaftor exposure work?
What is Elexacaftor-tezacaftor-ivacaftor exposure used for?
Who makes Elexacaftor-tezacaftor-ivacaftor exposure?
What drug class is Elexacaftor-tezacaftor-ivacaftor exposure in?
What development phase is Elexacaftor-tezacaftor-ivacaftor exposure in?
What are the side effects of Elexacaftor-tezacaftor-ivacaftor exposure?
What does Elexacaftor-tezacaftor-ivacaftor exposure target?
Related
- Drug class: All CFTR potentiator drugs
- Target: All drugs targeting CFTR
- Manufacturer: Jennifer Taylor-Cousar — full pipeline
- Therapeutic area: All drugs in Respiratory
- Indication: Drugs for Cystic fibrosis