Last reviewed · How we verify
Impact of Elexacaftor-tezacaftor-ivacaftor Triple Combination CFTR Therapy on Sinus Disease: Quantitative Sinus Computed Tomography, Patient Reported Outcomes and Cellular and Molecular Changes
The study's main goal is to observe how effective elexacaftor-tezacaftor-ivacaftor is for improving the symptoms and signs of CF-related sinus disease.
Details
| Lead sponsor | Jennifer Taylor-Cousar |
|---|---|
| Status | UNKNOWN |
| Enrolment | 31 |
| Start date | 2019-09-05 |
| Completion | 2022-07 |
Conditions
- Cystic Fibrosis
Interventions
- Elexacaftor-tezacaftor-ivacaftor exposure
Primary outcomes
- Change in Sinus CT opacification. — Change in Sinus CT opacification between the initial and 6 month visits.
Calculated from an automated quantification of the size of sinuses.
Countries
United States