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Benzocaine oral gel 20%
Benzocaine oral gel 20% is a Local anesthetic Small molecule drug developed by Dina Youssef Attia. It is currently FDA-approved for Topical anesthesia for minor mouth and gum irritations, sore throat, and oral pain relief.
Benzocaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.
Benzocaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses. Used for Topical anesthesia for minor mouth and gum irritations, sore throat, and oral pain relief.
At a glance
| Generic name | Benzocaine oral gel 20% |
|---|---|
| Sponsor | Dina Youssef Attia |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Pain management / Oral care |
| Phase | FDA-approved |
Mechanism of action
Benzocaine works by reversibly inhibiting sodium influx through nerve cell membranes, which stabilizes the neuronal membrane and prevents depolarization. This action suppresses the generation and propagation of action potentials in sensory nerves, resulting in local anesthesia. When applied topically as an oral gel, it numbs the oral mucosa and provides pain relief for minor mouth irritations.
Approved indications
- Topical anesthesia for minor mouth and gum irritations, sore throat, and oral pain relief
Common side effects
- Methemoglobinemia
- Local irritation or burning
- Allergic contact dermatitis
- Temporary numbness of throat
Key clinical trials
- Efficacy of Coconut Gel Compared to Corticosteroid Gel in the Management of Oral Lichen Planus (PHASE4)
- Pain Reduction Using Vibration and Topical Anesthesia (EARLY_PHASE1)
- Clinical Efficacy of In-office Bleaching With Different Concentrations of Hydrogen Peroxide (NA)
- Low Intensity Pulsed Ultrasound Versus Low Level Laser Therapy Post Dental Implant (NA)
- Effect of Intraarticular Injection of Tenoxicam and Hyaluronic Acid Versus Platelet-Rich Plasma and Hyaluronic Acid in Temporomandibular Joint Internal Derangement (PHASE1, PHASE2)
- Effectiveness of Pre-administered Natural Sweet-tasting Solution (Honey) for Decreasing Pain of Needle Insertion (NA)
- Buzzy System Compared to Topical Anaesthesia During Infiltration Injection in Children. (NA)
- Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel. (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Benzocaine oral gel 20% CI brief — competitive landscape report
- Benzocaine oral gel 20% updates RSS · CI watch RSS
- Dina Youssef Attia portfolio CI
Frequently asked questions about Benzocaine oral gel 20%
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Related
- Drug class: All Local anesthetic drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Dina Youssef Attia — full pipeline
- Therapeutic area: All drugs in Pain management / Oral care
- Indication: Drugs for Topical anesthesia for minor mouth and gum irritations, sore throat, and oral pain relief
- Compare: Benzocaine oral gel 20% vs similar drugs
- Pricing: Benzocaine oral gel 20% cost, discount & access