Last reviewed · How we verify
NCT06700434
Clinical Efficacy of In-office Bleaching With Different Concentrations of Hydrogen Peroxide
NA trial testing Bleaching treatment in Tooth Discoloration in 80 participants. Completed in 15 March 2024.
15 October 2023
Quick facts
| Lead sponsor | Gazi University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 11 September 2023 |
| Primary completion | 15 October 2023 |
| Estimated completion | 15 March 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Bleaching treatment
Conditions studied
- Tooth Discoloration — all drugs for Tooth Discoloration →
Sponsor
Gazi University
Who can join
Adults 21 to 28, any sex, with Tooth Discoloration. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Objective: The study evaluated the longevity, effectiveness, sensitivity and impact on the oral health-related quality of life of in-office dental bleaching using low, medium, and high concentrate hydrogen peroxide. Material and Methods: Randomized, parallel, and double-blinded clinical trial was performed with 54 participants using18% hydrogen peroxide (HP), 20%HP, and 40%HP in-office bleaching agent. Tooth color was evaluated at baseline, after the 1st session bleaching, after the 2st session bleaching and 6 months (T5) after finishing the bleaching using spectrophotometer. Tooth sensitivity was measured with the Visual Analog Scale at baseline, immediately after bleaching, after 1 day, and after 7 days. The impact on quality of life was evaluated using the Oral Health Impact Profile (OHIP) questionnaire at baseline, and 6 months after bleaching.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Clinical evaluation of in-office bleaching with low, medium, and high concentrate hydrogen peroxide: a 6-month a double-blinded randomized controlled trial.
Altınışık H, Nezir M. · · 2025 · cited 2× · PMID 40259078 · DOI 10.1007/s00784-025-06348-8
Verify or expand the search:
- PubMed search for NCT06700434
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Tooth Discoloration
Currently open trials in the same condition.
- NCT06532526 — Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching. · NA · recruiting
- NCT06125132 — Evaluation of 2-year Clinical Performance of Two Different Single Color Universal Composite Resin Restorative Materials. · NA · active not recruiting
- NCT04346849 — Tooth Discoloration Induced by Pulpotomy Materials · NA · active not recruiting
Other Gazi University trials
Trials by the same sponsor.
- NCT07500857 — Gamification in Stoma Care Education for Nursing Students · NA · not yet recruiting
- NCT07471737 — Patient Safety and Medical Errors in Nursing Education: Learning by Doing and Experiencing With Simulated Patients · NA · not yet recruiting
- NCT07440563 — Auricular Vagus Nerve Stimulation Combined With Rehabilitation in Parkinson's Disease · NA · enrolling by invitation
- NCT07496398 — Median and Ulnar Nerve Function in Tattoo Artists · recruiting
- NCT07471386 — Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06700434 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gazi University
- Last refreshed: 22 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06700434.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing