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Discoid lupus erythematosus
Approved treatments
- Flucorticin
- Aclovate
- Hydroxychloroquine Sulfate · Sanofi
Hydroxychloroquine Sulfate works by interfering with the replication of malaria parasites and modulating the immune system to treat autoimmune diseases. - Cordran · Aqua Pharms
- Cutivate · Teva Pharm
- Topicort · Taro
- Derma-Smoothe/Fs · Eurofarma
- Cloderm · Legacy Pharma
- Cortone
- Ultravate · Ranbaxy
Ultravate works by binding to the glucocorticoid receptor, triggering a cascade of anti-inflammatory effects that reduce skin inflammation. - Diprolene · Merck & Co.
Diprolene works by binding to the glucocorticoid receptor in the skin, which reduces inflammation and suppresses the immune system. - Verdeso · Padagis Us
- Betamethasone Valerate · Fougera Pharms Inc
- Decadron · Generic (originally Merck)
- Flonase · GSK (GlaxoSmithKline)
- Nasonex · University of Alberta
- Medrol · Generic (originally Upjohn/Pfizer)
Potent synthetic glucocorticoid with 5x hydrocortisone potency and minimal mineralocorticoid activity, used for severe inflammatory conditions. - Betamethasone 17-Benzoate
- Cortef · Generic (originally Merck/Upjohn)
- Rodinolone
- Flixotide · Mundipharma Research Limited
- Fluticason · Creighton University
- Aristospan · Ethypharm
- Lidex
- Aralen · Sanofi
Aralen works by accumulating in the acidic compartments of the malaria parasite, disrupting its metabolism and ultimately leading to its death. - Halog · Sun Pharma
- Dermatop · Bausch Health
- Hydroxychloroquine Sulfate · Advanz
Hydroxychloroquine Sulfate works by interfering with the replication of malaria parasites and reducing inflammation in the body. - Elocon · Merck & Co.
Elocon works by binding to the progesterone receptor, which reduces inflammation and immune response in the body. - Psorcon · Pfizer
- Cyclocort · Astellas Pharma
- Betametasone
Betamethasone works by binding to the glucocorticoid receptor, which then triggers a series of downstream effects that reduce inflammation and suppress the immune system. - Cortisol · University of Zurich
- Prelone · Generic (originally Schering)
- prednisolon · Hannover Medical School
- Methylprednisolon · Leiden University Medical Center
- Hydroxychloroquin · Children's Hospital of Fudan University
- MOMETASONE
12.1 Mechanism of Action Mometasone furoate nasal spray is a corticosteroid demonstrating potent anti-inflammatory properties. The precise mechanism of corticosteroid action on allergic rhinitis is not known. Corticosteroids have been shown to have a wide range of effects on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation. In two clinical studies utilizing nasal antigen challenge, mometasone furoate nasal spray decreased some markers of the early- and late-phase allergic response. These observations included decreases (vs. placebo) in histamine and eosinophil cationic protein levels, and reductions (vs. baseline) in eosinophils, neutrophils, and epithelial cell adhesion proteins. The clinical significance of these findings is not known. The effect of mometasone furoate nasal spray on nasal mucosa following 12 months of treatment was examined in 46 patients with allergic rhinitis. There was no evidence of atrophy and there was a marked reduction in intraepithelial eosinophilia and inflammatory cell infiltration (e.g., eosinophils, lymphocytes, monocytes, neutrophils, and plasma cells).
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Discoid lupus erythematosus patent landscape — cliff calendar, originator estates, attackable patents
- Discoid lupus erythematosus treatment landscape brief
- Discoid lupus erythematosus treatment updates RSS
Frequently asked questions about Discoid lupus erythematosus
What drugs treat Discoid lupus erythematosus?
Tracked treatments include Flucorticin, Aclovate, Hydroxychloroquine Sulfate, Cordran, Cutivate, Topicort, Derma-Smoothe/Fs, Cloderm.
What is the treatment for Discoid lupus erythematosus?
Standard treatment for Discoid lupus erythematosus includes Flucorticin, Aclovate, Hydroxychloroquine Sulfate, Cordran, Cutivate. See the treatment landscape page for first-line, second-line and salvage options.
Related
- Treatment landscape: Discoid lupus erythematosus patent cliff · Discoid lupus erythematosus CI report
- Treatment: Flucorticin
- Treatment: Aclovate
- Treatment: Hydroxychloroquine Sulfate · Sanofi
- Treatment: Cordran · Aqua Pharms
- Treatment: Cutivate · Teva Pharm
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing