Prozac · Neuroscience · revenue 1000.0 Fluoxetine inhibits CNS neuronal uptake of serotonin, though exact mechanism unknown.
Cyramza · Oncology · revenue 900 Cyramza blocks the VEGFR2 receptor, which is involved in cancer cell growth and spread.
Omvoh · Immunology · revenue 800 MIRIKIZUMAB blocks the activity of Interleukin-23, a protein involved in inflammation.
Retevmo · Oncology · revenue 700 Retevmo works by blocking the activity of the RET protein, which is involved in the growth and spread of cancer cells.
Emgality · Neuroscience · revenue 500 Emgality works by binding to calcitonin gene-related peptide 1 (CGRP1), preventing it from triggering migraine attacks.
Strattera · Neuroscience Strattera works by blocking the reabsorption of norepinephrine in the brain, allowing more of this neurotransmitter to be available for use.
Portrazza · Oncology Portrazza works by blocking the epidermal growth factor receptor (EGFR) protein, which is involved in cancer cell growth and proliferation.