Eli Lilly (LLY)

Quick facts

Marketed products

• Mounjaro · Metabolic · revenue 15530
  Tirzepatide is a dual GIP and GLP-1 receptor agonist with C20 fatty diacid for albumin binding.
• Trulicity · Metabolic · revenue 7200
  Dulaglutide activates GLP-1 receptors, increasing insulin release and decreasing glucagon secretion and gastric emptying.
• Verzenio · Oncology · revenue 3700
  Abemaciclib inhibits CDK4 and CDK6, blocking Rb phosphorylation and G1/S cell cycle progression.
• Taltz · Immunology · revenue 2700
  Humanized IgG4 monoclonal antibody that selectively binds IL-17A cytokine and inhibits its interaction with IL-17 receptor.
• Humalog · Metabolic · revenue 2200
  Humalog works by mimicking the natural hormone insulin to help cells absorb glucose from the bloodstream.
• Olumiant · Immunology · revenue 1200
• Prozac · Neuroscience · revenue 1000.0
  Fluoxetine inhibits CNS neuronal uptake of serotonin, though exact mechanism unknown.
• Cyramza · Oncology · revenue 900
  Cyramza blocks the VEGFR2 receptor, which is involved in cancer cell growth and spread.
• Omvoh · Immunology · revenue 800
  MIRIKIZUMAB blocks the activity of Interleukin-23, a protein involved in inflammation.
• Retevmo · Oncology · revenue 700
  Retevmo works by blocking the activity of the RET protein, which is involved in the growth and spread of cancer cells.
• Emgality · Neuroscience · revenue 500
  Emgality works by binding to calcitonin gene-related peptide 1 (CGRP1), preventing it from triggering migraine attacks.
• Zyprexa · Neuroscience · revenue 300
• Dymelor · Metabolic
• Strattera · Neuroscience
  Strattera works by blocking the reabsorption of norepinephrine in the brain, allowing more of this neurotransmitter to be available for use.
• Kafocin · Metabolic
• Cephalotin · Metabolic
• Kefadol · Immunology
  Kefadol works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death.
• Cinobac · Infectious Disease
• Pagitane · Neuroscience
• Digicor · Cardiovascular
• Metocurine · Neuroscience
• KISUNLA · Other
• Metholone · Oncology
• Cymbalta · Metabolic
  Potentiates serotonergic and noradrenergic activity in the CNS through unknown exact mechanisms.
• Ly-Cov016 · Infectious Disease
• Eramin · Oncology
• Inluriyo · Oncology
  Inluriyo works by blocking estrogen receptors on cancer cells, preventing them from growing and spreading.
• Decabid · Cardiovascular
• Humulin · Metabolic
  Humulin works by binding to insulin receptors on cells, triggering a cascade of signals that lower blood glucose levels.
• Reyvow · Neuroscience
  Reyvow works by binding to the 5-HT1F receptor, blocking pain signals in the brain.
• Moxam · Metabolic
• Ebglyss · Immunology
  Ebglyss works by binding to interleukin-13, a protein that promotes inflammation in the skin.
• EBGLYSS · Other
• Kappadione · Hematology
• Menadion · Other
• Dicurin Procaine · Other
• OMVOH · Immunology
• Portrazza · Oncology
  Portrazza works by blocking the epidermal growth factor receptor (EGFR) protein, which is involved in cancer cell growth and proliferation.
• Lartruvo · Oncology
• Quinidine Gluconate · Neuroscience
  Quinidine Gluconate works by blocking the M2 muscarinic acetylcholine receptor, which helps regulate heart rhythm.