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Kefadol (CEFAMANDOLE NAFATE)
Kefadol (generic name: CEFAMANDOLE NAFATE) is a cefamandole nafate Small molecule drug developed by Eli Lilly. It is currently FDA-approved (first approved 1978).
Kefadol works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death.
Kefadol, also known as cefamandole nafate, is a small molecule antibiotic in the cefamandole class. Originally developed by Lilly and currently owned by the same company, it was FDA approved in 1978. Although its target and exact mechanism of action are unknown, it is used to treat various bacterial infections. Kefadol is now off-patent and available as a generic medication. As with any antibiotic, it is essential to use Kefadol judiciously to prevent the development of antibiotic-resistant bacteria.
At a glance
| Generic name | CEFAMANDOLE NAFATE |
|---|---|
| Sponsor | Eli Lilly |
| Drug class | cefamandole nafate |
| Target | Bacterial penicillin-binding protein |
| Modality | Small molecule |
| Therapeutic area | Immunology |
| Phase | FDA-approved |
| First approval | 1978 |
Mechanism of action
Imagine the bacterial cell wall as a strong, protective shield. Kefadol disrupts the process of building this shield, causing the bacteria to weaken and eventually die. This allows the body's immune system to fight off the infection more effectively.
Approved indications
Common side effects
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Kefadol CI brief — competitive landscape report
- Kefadol updates RSS · CI watch RSS
- Eli Lilly portfolio CI
Frequently asked questions about Kefadol
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Related
- Drug class: All cefamandole nafate drugs
- Target: All drugs targeting Bacterial penicillin-binding protein
- Manufacturer: Eli Lilly — full pipeline
- Therapeutic area: All drugs in Immunology
- Compare: Kefadol vs similar drugs
- Pricing: Kefadol cost, discount & access