Afstyla® · Hematology Afstyla is a recombinant antithrombin III-free factor VIII that replaces deficient clotting factor VIII to restore hemostasis in patients with hemophilia A.
Filsuvez · Hematology Monoclonal antibody that inhibits activated Factor XII (FXIIa), preventing the generation of bradykinin which causes angioedema attacks.
Haemocomplettan® P · Hematology Haemocomplettan® P is a prothrombin complex concentrate (PCC) that replaces deficient vitamin K-dependent clotting factors to restore coagulation capacity.
IgPro · Immunology IgPro is an intravenous immunoglobulin (IVIG) product that provides passive immunity by supplying pooled human antibodies to help fight infections and modulate immune responses.
IgPro20 · Immunology IgPro20 is a subcutaneous immunoglobulin replacement therapy that provides passive immunity by delivering polyclonal human immunoglobulins to patients with primary immunodeficiency.
Alpha-1 antitrypsin (AAT) · Pulmonology / Genetic / Rare Disease Alpha-1 antitrypsin (AAT) is a protease inhibitor that replaces deficient endogenous AAT to prevent neutrophil elastase-mediated tissue destruction in the lungs and other organs.
BE1116 · Hematology BE1116 is a recombinant human albumin-von Willebrand factor (VWF) fusion protein that replaces or augments deficient VWF function in von Willebrand disease.
Beriplex® P/N (Kcentra) · Hematology / Anticoagulation reversal Beriplex P/N is a prothrombin complex concentrate that replaces deficient vitamin K-dependent clotting factors to rapidly reverse warfarin anticoagulation.
CSL312 · Cardiovascular CSL312 is an apolipoprotein A-I (apoA-I) mimetic that increases HDL cholesterol and promotes reverse cholesterol transport.
Factor IX (FIX) · Hematology Factor IX is a vitamin K-dependent clotting factor that replaces deficient or dysfunctional Factor IX to restore the intrinsic coagulation pathway and enable normal blood clot formation.
FXIII Concentrate (Human) · Hematology FXIII Concentrate replaces deficient coagulation Factor XIII to restore normal blood clot cross-linking and stabilization.
Higher-volume C1-esterase inhibitor · Immunology / Rare Disease A higher-concentration formulation of C1-esterase inhibitor that suppresses activation of the contact system and complement cascade to prevent angioedema attacks.
IgPro20 (high dose) · Immunology IgPro20 is a subcutaneous immunoglobulin replacement therapy that provides passive immunity by delivering polyclonal human immunoglobulins to treat primary immunodeficiency.
IgPro20 (low dose) · Immunology IgPro20 is a subcutaneous immunoglobulin replacement therapy that provides passive immunity by delivering polyclonal human immunoglobulins to patients with primary immunodeficiency.
Low-volume C1-esterase inhibitor · Immunology / Rare disease Low-volume C1-esterase inhibitor (C1-INH) replaces or augments deficient or dysfunctional C1-esterase inhibitor protein to suppress excessive contact system and complement activation.
rIX-FP · Hematology rIX-FP is a recombinant, humanized monoclonal antibody that targets factor VIII to prevent bleeding in patients with hemophilia A.
rVIII-SingleChain · Hematology rVIII-SingleChain is a recombinant single-chain factor VIII that replaces deficient clotting factor VIII to restore hemostasis in hemophilia A patients.
Phase 2 pipeline
Biostate® [RP] · Immunology Biostate is a recombinant human C1 esterase inhibitor used to treat hereditary angioedema.
Biostate® [SP] · Immunology Biostate is a recombinant human C1 esterase inhibitor used to treat hereditary angioedema.
CSL_112 · Immunology CSL_112 is a recombinant human monoclonal antibody that targets the complement system.