viral vector vaccine
This page covers all viral vector vaccine drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting SARS-CoV-2 spike protein, Hepatitis C virus antigens, Ebola virus glycoprotein (GP).
Targets
SARS-CoV-2 spike protein · Hepatitis C virus antigens · Ebola virus glycoprotein (GP) · Filovirus glycoproteins (Ebola virus GP, Marburg virus GP) · Ebola virus glycoprotein (ZEBOV) · SARS-CoV-2 Omicron variant spike protein · Ebola virus glycoprotein (EBOV GP) · HIV-1 gp120 envelope glycoprotein · RSV prefusion F protein · Mycobacterium tuberculosis antigens (Ag85A, TB10.4)
Marketed (6)
- batch 3 of Ad5-nCoV · Jiangsu Province Centers for Disease Control and Prevention · Immunology / Infectious Disease
Ad5-nCoV is a recombinant adenovirus type 5 vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate immune responses against COVID-19. - TT · CanSino Biologics Inc. · Immunology / Infectious Disease
TT is a recombinant adenovirus type 5 vector-based vaccine that expresses the SARS-CoV-2 spike protein to elicit immune responses against COVID-19. - Hep-V Vax · University of Oxford · Immunology / Infectious Disease
Hep-V Vax is a viral vector-based vaccine that delivers hepatitis C viral antigens to stimulate immune responses against hepatitis C infection. - Intramuscularly administered Ad5-nCoV vaccine · Jiangsu Province Centers for Disease Control and Prevention · Immunology / Infectious Disease
An adenovirus type 5 (Ad5) vector vaccine delivers the SARS-CoV-2 spike protein gene intramuscularly to stimulate cellular and humoral immune responses against COVID-19. - Ad26.COV2.S vaccine · University Medical Center Groningen · Immunology / Infectious Disease
Ad26.COV2.S is a viral vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate immune responses against COVID-19. - batch 1 of Ad5-nCoV · Jiangsu Province Centers for Disease Control and Prevention · Immunology / Infectious Disease
Ad5-nCoV is a recombinant adenovirus type 5 vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate immune responses against COVID-19.
Phase 3 pipeline (21)
- AstraZeneca/Fiocruz · D'Or Institute for Research and Education · Immunology / Infectious Disease
This is the AstraZeneca/Fiocruz COVID-19 vaccine (ChAdOx1 nCoV-19, Covishield), which uses a replication-deficient chimpanzee adenovirus vector carrying the SARS-CoV-2 spike protein gene to induce immune responses. - BBV154(Intranasal) & covaxin · Bharat Biotech International Limited · Immunology / Infectious Disease
BBV154 is an intranasal booster vaccine designed to enhance immune response against SARS-CoV-2 when administered after Covaxin (inactivated COVID-19 vaccine) priming. - Astrazenica vaccine · Samia Hassan El-Shishtawy · Immunology / Infectious Disease
The AstraZeneca COVID-19 vaccine (ChAdOx1 nCoV-19) uses a replication-deficient chimpanzee adenovirus vector to deliver the SARS-CoV-2 spike protein gene, triggering immune responses against the virus. - ChAdOx1-S vaccine · Vaxxinity, Inc. · Immunology / Infectious Disease
ChAdOx1-S is a viral vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate adaptive immune responses against COVID-19. - Sputnik Light · Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation · Immunology / Infectious Disease
Sputnik Light is a viral vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate adaptive immune responses against COVID-19. - Ad26.COV2.S · National Institute of Allergy and Infectious Diseases (NIAID) · Immunology / Infectious Disease
Ad26.COV2.S is a viral vector vaccine that delivers genetic instructions for the SARS-CoV-2 spike protein to stimulate immune responses against COVID-19. - Ad26.ZEBOV 2*10^10 (vp) · Janssen Vaccines & Prevention B.V. · Immunology / Infectious Disease
Ad26.ZEBOV is a replication-incompetent adenovirus serotype 26 vector expressing the Ebola virus glycoprotein that primes the immune system to recognize and respond to Ebola virus. - MVA-BN-Filo 5*10^7 Inf. U. · Janssen Vaccines & Prevention B.V. · Immunology / Infectious Disease
MVA-BN-Filo is a recombinant modified vaccinia Ankara (MVA) vaccine expressing Filovirus glycoproteins that primes the immune system to recognize and respond to Ebola and Marburg viruses. - ChAdOx1 nCoV-19 · EuBiologics Co.,Ltd · Immunology / Infectious Disease
ChAdOx1 nCoV-19 is a viral vector vaccine that delivers the SARS-CoV-2 spike protein gene into cells to trigger an immune response against COVID-19. - Ad26.ZEBOV-Batch #2 · Crucell Holland BV · Immunology / Infectious Disease
Ad26.ZEBOV is a replication-incompetent adenovirus serotype 26 vector expressing the Ebola virus glycoprotein that primes the immune system to recognize and respond to Ebola virus infection. - Ad26.ZEBOV, MVA-BN-Filo vaccine · London School of Hygiene and Tropical Medicine · Immunology / Infectious Disease
A two-dose heterologous prime-boost vaccine regimen that uses recombinant adenovirus 26 (Ad26) and modified vaccinia Ankara (MVA) vectors expressing Ebola virus glycoprotein to elicit cellular and humoral immune responses against Ebola virus. - Ad26.ZEBOV-Batch #1 · Crucell Holland BV · Immunology / Infectious Disease
Ad26.ZEBOV is a replication-incompetent adenovirus serotype 26 vector expressing the Ebola virus glycoprotein that primes the immune system to recognize and respond to Ebola virus infection. - AdCLD-CoV19-1 OMI · Cellid Co., Ltd. · Immunology / Infectious Disease
AdCLD-CoV19-1 OMI is an adenoviral vector-based vaccine designed to elicit immune responses against Omicron variant SARS-CoV-2 antigens. - Ad26.ZEBOV 0.8*10^10 (vp) · Janssen Vaccines & Prevention B.V. · Immunology / Infectious Disease
Ad26.ZEBOV is a replication-incompetent adenovirus serotype 26 vector expressing the Ebola virus glycoprotein that primes the immune system to recognize and respond to Ebola virus infection. - Ad26.ZEBOV-Batch #3 · Crucell Holland BV · Immunology / Infectious Disease
Ad26.ZEBOV is a replication-incompetent adenovirus serotype 26 vector expressing the Ebola virus glycoprotein, designed to elicit immune responses against Ebola virus. - ChAdOx1 nCoV-19 single dose + paracetamol · University of Oxford · Immunology / Infectious Disease
ChAdOx1 nCoV-19 is a viral vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate immune responses against COVID-19, combined with paracetamol for symptomatic relief. - ChAdOx1 nCoV-19 two dose + paracetamol · University of Oxford · Immunology / Infectious Disease
ChAdOx1 nCoV-19 is a viral vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate immune responses against COVID-19. - AZD 1222 · University Medicine Greifswald · Immunology / Infectious Disease
AZD1222 is a viral vector vaccine that delivers genetic instructions for the SARS-CoV-2 spike protein to stimulate immune responses against COVID-19. - ALVAC(2)120(B,MN)GNP (vCP1452) · National Institute of Allergy and Infectious Diseases (NIAID) · Immunology / Infectious Disease
ALVAC(2)120(B,MN)GNP is a recombinant canarypox virus-based vaccine that expresses HIV-1 gp120 and other viral antigens to elicit cellular and humoral immune responses against HIV-1. - Ad26.RSV.preF-based vaccine · Janssen Vaccines & Prevention B.V. · Immunology / Infectious Disease
An adenovirus serotype 26 (Ad26)-based vaccine expressing the respiratory syncytial virus (RSV) prefusion F protein to elicit immune responses against RSV infection. - BBV154 Intranasal Vaccine · Bharat Biotech International Limited · Immunology / Infectious Disease
BBV154 is an intranasal recombinant vaccine that stimulates mucosal and systemic immune responses against SARS-CoV-2 by delivering viral antigens directly to respiratory tract tissues.
Phase 2 pipeline (2)
- AERAS-402 3 x 10^8 vp · Aeras · Immunology / Infectious Disease
AERAS-402 is a replication-deficient adenovirus vector vaccine that expresses Mycobacterium tuberculosis antigens to stimulate immune responses against tuberculosis. - Astra Zeneca COVID-19 vaccine · Vinbiocare Biotechnology Joint Stock Company · Immunology
This viral vector vaccine delivers genetic instructions for the SARS-CoV-2 spike protein to stimulate adaptive immune responses against COVID-19.
Phase 1 pipeline (1)
- Ad26.Filo · Janssen Vaccines & Prevention B.V. · Infectious Disease
Ad26.Filo is a viral vector vaccine that targets filoviruses.