Thyroid hormone replacement

This page covers all Thyroid hormone replacement drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Thyroid hormone receptor alpha and beta (TRα, TRβ), Thyroid hormone receptors (TR-alpha, TR-beta), Thyroid receptor proteins attached to DNA.

Targets

Thyroid hormone receptor alpha and beta (TRα, TRβ) · Thyroid hormone receptors (TR-alpha, TR-beta) · Thyroid receptor proteins attached to DNA · Thyroid hormone receptors (TR-alpha and TR-beta) · Thyroid hormone receptor (TR-alpha and TR-beta) · Thyroid hormone receptor (TR-alpha, TR-beta) · Thyroid hormone receptor alpha (TRα), Thyroid hormone receptor beta (TRβ) · Thyroid hormone receptor

Marketed (11)

• Liothyronine and Levothyroxine · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Endocrinology
  Liothyronine (T3) and levothyroxine (T4) are thyroid hormones that bind to thyroid hormone receptors to increase metabolic rate and regulate cellular energy production.
• Thyroid hormone · Merck Sharp & Dohme LLC · Endocrinology
  Thyroid hormone replaces or supplements endogenous thyroid hormones (T3 and T4) to restore normal metabolic function in hypothyroid patients.
• Levoxyl · Pfizer Inc. · Oncology
  Levothyroxine binds thyroid receptors in cell nuclei to activate gene transcription and protein synthesis.
• Levothyroxin-Na · Sanofi · Endocrinology
  Levothyroxine sodium is a synthetic thyroid hormone that replaces or supplements endogenous thyroid hormone to restore normal metabolic function.
• Euthyrox (levothyroxine) · University Medical Center Groningen · Endocrinology
  Levothyroxine is a synthetic thyroid hormone that replaces or supplements endogenous thyroid hormone to restore normal thyroid function.
• L-Thyroxine (tablet, per os) · Meyer Children's Hospital IRCCS · Endocrinology
  L-Thyroxine is a synthetic thyroid hormone that replaces or supplements endogenous thyroid hormone to restore normal metabolic function.
• Levothyroxine Tablet · University of California, Los Angeles · Endocrinology
  Levothyroxine is a synthetic thyroid hormone that replaces or supplements endogenous thyroid hormone to restore normal metabolic function.
• L-thyroxine (L-T4) · Oregon Health and Science University · Endocrinology
  L-thyroxine is a synthetic thyroid hormone that replaces or supplements endogenous thyroid hormone to restore normal metabolic function.
• L-thyroxin · University of Tartu · Endocrinology
  L-thyroxine is a synthetic thyroid hormone that replaces or supplements endogenous thyroid hormone to restore normal metabolic function.
• Tirosint®-SOL · IBSA Institut Biochimique SA · Endocrinology
  Tirosint-SOL is a liquid formulation of levothyroxine that replaces deficient thyroid hormone to restore normal thyroid function.
• Cytomel · Pfizer Inc. · Other
  Thyroid hormones bind nuclear receptors to control DNA transcription and protein synthesis.

Phase 3 pipeline (3)

• LT3 (liothyronine) · M. Medici · Endocrinology
  Liothyronine is a synthetic form of triiodothyronine (T3) that binds to thyroid hormone receptors to increase metabolic rate and cellular energy production.
• Reference(Stillen tab.) · Daewon Pharmaceutical Co., Ltd. · Endocrinology
  Stillen is a medication used to treat hypothyroidism.
• Levothyroxine Pill · Al-Kindy College of Medicine · Endocrinology
  Levothyroxine is a synthetic thyroid hormone that replaces or supplements endogenous thyroid hormone to restore normal metabolic function.

Phase 2 pipeline (1)

• Levothyroxine sodium new formulation · Takeda · Endocrinology
  Levothyroxine sodium acts on the thyroid hormone receptor.