Muscarinic receptor agonist

This page covers all Muscarinic receptor agonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Muscarinic acetylcholine receptor (M3), M1, M4, Muscarinic acetylcholine receptors (M3, M4).

Targets

Muscarinic acetylcholine receptor (M3) · M1, M4 · Muscarinic acetylcholine receptors (M3, M4) · Muscarinic M3 receptor · Muscarinic acetylcholine receptors (M1, M3)

Marketed (1)

• Pilocarpine Ophthalmic Solution · Maastricht University Medical Center · Ophthalmology
  Pilocarpine is a muscarinic acetylcholine receptor agonist that stimulates parasympathetic activity in the eye to increase aqueous humor outflow and reduce intraocular pressure.

Phase 3 pipeline (4)

• Xanomeline Enteric Capsule · Bristol-Myers Squibb · Neurology
  Xanomeline is a muscarinic receptor agonist that targets the M1 and M4 subtypes.
• Low dose pilocarpine · Ocuphire Pharma, Inc. · Ophthalmology
  Low-dose pilocarpine is a muscarinic acetylcholine receptor agonist that stimulates parasympathetic activity to increase aqueous humor outflow and reduce intraocular pressure.
• Pilocarpine HCl · Allergan · Ophthalmology / Otolaryngology
  Pilocarpine HCl is a muscarinic acetylcholine receptor agonist that stimulates parasympathetic activity to increase salivary and lacrimal gland secretion.
• Aceclidine ophthalmic solution · LENZ Therapeutics, Inc · Ophthalmology
  Aceclidine is a cholinergic agonist that stimulates muscarinic receptors in the eye to increase accommodation and improve near vision.