immunomodulator

This page covers all immunomodulator drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting T-cell maturation pathway / thymic differentiation, Myelin basic protein, TLR7, TLR8.

Targets

T-cell maturation pathway / thymic differentiation · Myelin basic protein · TLR7, TLR8 · Cereblon · T cell receptor · Complement receptor 3 (CR3), Dectin-1 · TNF-alpha · Unknown · CD25 · Interferon-gamma

Marketed (6)

• MED ON plus · IRCCS Istituto delle Scienze Neurologiche di Bologna · Neurology
  MED ON plus is a medication used to treat multiple sclerosis.
• Thymosin Alpha · Second Affiliated Hospital, School of Medicine, Zhejiang University · Immunology
  Thymosin Alpha is an immunomodulatory peptide that enhances T-cell maturation and immune function by promoting thymic development and activation of immune cells.
• Thymosin Alpha 1 · Xuanwu Hospital, Beijing · Immunology
  Thymosin Alpha 1 is an immunomodulatory peptide that enhances T-cell maturation and immune function by promoting thymic differentiation and activation of immune cells.
• Anaferon for Children · Materia Medica Holding · Immunology / Virology
  Anaferon for Children is an immunomodulatory agent that stimulates interferon production and enhances innate immune responses to combat viral infections.
• Tailored Group · Beijing Children's Hospital · Immunology
  The drug works by modulating the immune system to treat various conditions.
• Advanced Medical Therapy · Hadassah Medical Organization · Immunology
  Advanced Medical Therapy works by modulating the immune system to treat various conditions.

Phase 3 pipeline (12)

• High Dose Maolactin · RDC Clinical Pty Ltd · Infectious Diseases
  High Dose Maolactin is an immunomodulatory agent that modulates the immune system to treat various conditions.
• copolymer 1 · National Center for Research Resources (NCRR) · Neurology
  Copolymer 1 is a synthetic polymer that works by inducing an immune response against the myelin basic protein, thereby reducing inflammation in the central nervous system.
• subcutaneous immunotherapy · ALK-Abelló A/S · Immunology
  Subcutaneous immunotherapy involves administering allergens or allergen extracts under the skin to build tolerance and reduce allergic reactions.
• Western Medicine · Chang Gung Memorial Hospital · Oncology
  Western medicine works by targeting the immune system to treat various conditions.
• imiquimod cream, 3.75% · Actavis Mid-Atlantic LLC · Dermatology
  Imiquimod cream works by activating the immune system to fight off abnormal cell growth.
• TJ202, Lenalidomide and Dexamethasone · TJ Biopharma Co., Ltd. · Oncology
  Lenalidomide is an immunomodulatory drug that stimulates the immune system to attack cancer cells, while dexamethasone is a corticosteroid that has anti-inflammatory and immunosuppressive properties.
• thymalfasin (thymosin alpha 1) · SciClone Pharmaceuticals · Immunology
  Thymalfasin (thymosin alpha 1) is a peptide that stimulates the immune system by activating T cells and natural killer cells.
• WF10 · Oxo Chemie GmbH · Immunology
  WF10 is a stable, diluted solution of dihydroxyethyl disulfide that acts as an immunomodulator and antioxidant to enhance immune function and reduce inflammatory responses.
• glutamine combined with thalidomide · Air Force Military Medical University, China · Oncology
  Glutamine has been shown to have immunomodulatory effects, while thalidomide is known for its antiangiogenic and immunomodulatory properties.
• Betaglucin soluble gel 0.2% · Centro de Investigaciones Medicas y Ensayos Clinicos Dr Italo Fabbri · Immunology / Oncology
  Betaglucin is a beta-glucan immunomodulator that enhances innate immune responses by activating pattern recognition receptors on immune cells.
• Krestin (PSK) · Hokuriku-Kinki Immunochemotherapy Study Group · Oncology
  PSK (polysaccharide K) is a fungal-derived immunomodulator that enhances immune cell activity to support anti-tumor responses.
• Thalidomide (100mg) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Oncology
  Thalidomide acts as an immunomodulatory agent, inhibiting the release of tumor necrosis factor-alpha (TNF-alpha) and other pro-inflammatory cytokines.

Phase 2 pipeline (9)

• Drug: LYC-30937-EC · Lycera Corp. · Immunology
  LYC-30937-EC is an immunomodulatory drug.
• ALK Alutard 5-grasses · Lars Olaf Cardell · Allergy
  ALK Alutard 5-grasses is an immunotherapy that targets the CD25 antigen.
• Betaferon, BAY86-5046 · Bayer · Immunology
  Betaferon is an immunomodulatory drug that works by inhibiting the production of interferon-gamma, a cytokine involved in the immune response.
• ABR-215050, tasquinimod · Active Biotech AB · Oncology
  Tasquinimod is a quinoline-3-carboxamide derivative that modulates the immune system by targeting the S100A9 protein.
• Allergen immunotherapy · Rohr and Columbo Asthma, Allergy and Immunology Specialists, P.C. · Immunology
  Allergen immunotherapy works by gradually increasing exposure to specific allergens to build tolerance and reduce symptoms.
• DPK-060 · DermaGen AB · Dermatology
  DPK-060 is a topical treatment that modulates the immune response to reduce inflammation.
• Anti-IL2R AB · Astellas Pharma Inc · Immunology
  Anti-IL2R antibody
• Chinese Herbal Medication · Xiu-Min Li · Immunology
  Chinese herbal medication is used to modulate the immune system and reduce inflammation.
• Fumaric acids · Swiss Dermatology Network for Targeted Therapies · Dermatology
  Fumaric acid is thought to modulate the immune system by inhibiting the production of pro-inflammatory cytokines.