Cereblon — Drug Target

All drugs that target Cereblon — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

Immunomodulator · cereblon modulator

Phase 3 pipeline (1)

• TJ202, Lenalidomide and Dexamethasone · TJ Biopharma Co., Ltd. · Immunomodulator · Oncology
  Lenalidomide is an immunomodulatory drug that stimulates the immune system to attack cancer cells, while dexamethasone is a corticosteroid that has anti-inflammatory and immunosuppressive properties.

Phase 2 pipeline (1)

• CC-220 · Celgene · cereblon modulator · Immunology
  CC-220 is a small molecule that modulates the activity of cereblon, an E3 ubiquitin ligase, leading to the degradation of specific proteins involved in inflammation and immune responses.