What are Estrogen receptor agonist drugs?

Estrogen receptor agonist drugs are pharmacologic agents that share a common mechanism (typically targeting Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)). 5 are currently marketed, with 4 more in clinical development.

What are the marketed Estrogen receptor agonist drugs?

Marketed Estrogen receptor agonist drugs include Estriol Cream 0.1%, Vaginal estradiol tablets, estriol cream, estradiol valerat, Estradiol 0.01% Vag Cream.

Estrogen receptor agonist

5 marketed 4 in Phase 3

This page covers all Estrogen receptor agonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ), Estrogen receptor alpha (ERα), Estrogen receptor beta (ERβ), estrogen receptor.

Targets

Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) · Estrogen receptor alpha (ERα), Estrogen receptor beta (ERβ) · estrogen receptor

Marketed (5)

Estriol Cream 0.1% · Dr. August Wolff GmbH & Co. KG Arzneimittel · Gynecology / Menopause
Estriol is a weak estrogen that binds to estrogen receptors in vaginal and urogenital tissues to restore epithelial maturation and improve local tissue health.
Vaginal estradiol tablets · Johns Hopkins University · Women's Health / Gynecology
Vaginal estradiol tablets deliver estrogen directly to vaginal tissue to relieve symptoms of vaginal atrophy and genitourinary syndrome of menopause.
estriol cream · Hatice Tukenmez Kurnaz · Gynecology / Endocrinology
Estriol cream delivers the estrogen hormone estriol topically to provide localized or systemic estrogen replacement therapy.
estradiol valerat · farzaneh hojjat · Endocrinology
Estradiol valerate is an estrogen receptor agonist that binds to and activates estrogen receptors to provide hormone replacement therapy.
Estradiol 0.01% Vag Cream · TriHealth Inc. · Gynecology / Women's Health
Estradiol binds to estrogen receptors in vaginal tissue to restore local estrogen levels and alleviate symptoms of vaginal atrophy and genitourinary syndrome of menopause.

Phase 3 pipeline (4)

estradiol (Zesteem) · Renovo · Women's Health
Estradiol acts as an estrogen receptor agonist, mimicking the effects of the naturally occurring hormone estrogen in the body.
Estradiol (E2) · Martin Blomberg Jensen · Endocrinology
Estradiol binds to estrogen receptors (ERα and ERβ) in target tissues to modulate gene expression and produce estrogenic effects.
Generic Estradiol Vaginal Cream USP, 0.01% · Actavis Inc. · Gynecology / Menopause
Estradiol binds to estrogen receptors in vaginal tissue to restore local estrogen levels and alleviate symptoms of vaginal atrophy and urogenital dysfunction.
Estradiol (E2 0.3mg) · Bayer · Endocrinology / Women's Health
Estradiol is a naturally occurring estrogen that binds to estrogen receptors (ERα and ERβ) to modulate hormone-dependent physiological processes.