What are Combined oral contraceptive drugs?

Combined oral contraceptive drugs are pharmacologic agents that share a common mechanism (typically targeting Estrogen receptor and progesterone receptor). 17 are currently marketed, with 5 more in clinical development.

What are the marketed Combined oral contraceptive drugs?

Marketed Combined oral contraceptive drugs include Ethinylestradiol / Norethisterone, desogestrel/ethinyl estradiol, Phase 3 NOMAC-E2 "Batch A", Nomegestrol Acetate / Estradiol, Drospirenone / Estetrol, Ethinyl Estradiol + Desogestrel.

Combined oral contraceptive

17 marketed 5 in Phase 3

This page covers all Combined oral contraceptive drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Estrogen receptor and progesterone receptor, Progesterone receptor, estrogen receptor, Progesterone receptor, Estrogen receptor.

Targets

Estrogen receptor and progesterone receptor · Progesterone receptor, estrogen receptor · Progesterone receptor, Estrogen receptor · Estrogen receptor, progesterone receptor · Progesterone receptor, estrogen receptor alpha and beta · Progesterone receptor (levonorgestrel); estrogen receptor (ethinylestradiol) · Estrogen receptor; progesterone receptor · Estrogen receptor, progesterone receptor, mineralocorticoid receptor · Estrogen receptors (ER-α, ER-β) and progesterone receptors (PR); mineralocorticoid receptor antagonism · Estrogen receptor (ER), Progesterone receptor (PR)

Marketed (17)

Ethinylestradiol / Norethisterone · University of Edinburgh · Contraception / Reproductive Health
Ethinylestradiol and norethisterone work together as a combined oral contraceptive by suppressing ovulation through hormonal feedback on the hypothalamic-pituitary-ovarian axis.
desogestrel/ethinyl estradiol · Teva Branded Pharmaceutical Products R&D, Inc. · Contraception / Gynecology
Desogestrel/ethinyl estradiol is a combined oral contraceptive that prevents pregnancy by suppressing ovulation through progestin and estrogen activity.
Phase 3 NOMAC-E2 "Batch A" · Organon and Co · Contraception / Gynecology
NOMAC-E2 is a combined oral contraceptive containing norethisterone acetate (progestin) and ethinyl estradiol (estrogen) that prevents pregnancy through ovulation suppression and cervical mucus thickening.
Nomegestrol Acetate / Estradiol · University of Palermo · Contraception / Gynecology
Nomegestrol acetate and estradiol work together as a hormonal contraceptive by suppressing ovulation through progestin and estrogen activity.
Drospirenone / Estetrol · University of Palermo · Contraception / Women's Health
Drospirenone and estetrol work together as a hormonal contraceptive by suppressing ovulation through progestin and estrogen activity.
Ethinyl Estradiol + Desogestrel · Massachusetts General Hospital · Contraception / Reproductive Health
Ethinyl estradiol and desogestrel work together as a combined oral contraceptive by suppressing ovulation through hormonal feedback on the hypothalamic-pituitary-ovarian axis.
Levonorgestrel/Ethinyl Estradiol · Wyeth is now a wholly owned subsidiary of Pfizer · Contraception / Gynecology
This combination oral contraceptive suppresses ovulation by inhibiting the luteinizing hormone surge through progestin and estrogen feedback on the hypothalamic-pituitary axis.
placebo + ethinylestradiol/levonorgestrel · HRA Pharma · Contraception / Reproductive Health
Ethinylestradiol and levonorgestrel work together as a combined oral contraceptive to prevent ovulation and thicken cervical mucus, thereby preventing pregnancy.
Levonorgestrel and ethinylestradiol · IVI Madrid · Contraception / Reproductive Health
Levonorgestrel and ethinylestradiol is a combined oral contraceptive that prevents ovulation by suppressing gonadotropin hormones and altering cervical mucus and endometrial conditions.
Estetrol and Drospirenone · Ospedale Policlinico San Martino · Contraception
Estetrol and drospirenone work together as a hormonal contraceptive, with estetrol providing estrogenic activity and drospirenone providing progestagenic activity to prevent ovulation.
Ethinyl estradiol / dienogest · Helsinki University Central Hospital · Contraception / Gynecology
Ethinyl estradiol and dienogest work together as a combined oral contraceptive, suppressing ovulation through hormonal feedback on the hypothalamic-pituitary-ovarian axis.
OCR · Hoffmann-La Roche · Contraception / Gynecology
OCR is an oral contraceptive containing ethinylestradiol and norgestimate that prevents pregnancy by suppressing ovulation and altering cervical mucus.
OC - Drospirenone plus Ethynylestradiol · Federico II University · Contraception / Gynecology
Drospirenone and ethinylestradiol work together as an oral contraceptive by suppressing ovulation through progestin and estrogen activity.
Ethinylestradiol / Dienogest · University of Palermo · Contraception, Gynecology
Ethinylestradiol and dienogest work together as a combined oral contraceptive, suppressing ovulation through hormonal feedback on the hypothalamic-pituitary-ovarian axis.
ETHINYL ESTRADIOL AND LEVOGESTREL · FHI 360 · Contraception / Reproductive Health
This combination oral contraceptive prevents pregnancy by suppressing ovulation through hormonal inhibition of the hypothalamic-pituitary-ovarian axis.
Drospirenone and Ethinyl Estradiol tablets · Hansoh BioMedical R&D Company · Contraception / Gynecology
Drospirenone and ethinyl estradiol is a combined oral contraceptive that prevents pregnancy by suppressing ovulation through progestin and estrogen activity.
Estradiol+Drospirenone · Brigham and Women's Hospital · Contraception / Gynecology
Estradiol and drospirenone work together as a hormonal contraceptive by suppressing ovulation through negative feedback on the hypothalamic-pituitary-ovarian axis.

Phase 3 pipeline (5)

Mircette® · Teva Branded Pharmaceutical Products R&D, Inc. · Contraception / Gynecology
Mircette is a combined oral contraceptive that prevents pregnancy by suppressing ovulation through progestin and estrogen hormones.
Yasmin (EE30/DRSP, BAY86-5131) · Bayer · Women's Health
Yasmin is a combination oral contraceptive that works by inhibiting ovulation through the estrogen and progestin components.
Ethinylestradiol/levonorgestrel · Leiden University Medical Center · Contraception / Reproductive Health
Ethinylestradiol/levonorgestrel is a combined oral contraceptive that suppresses ovulation by inhibiting gonadotropin-releasing hormone (GnRH) and preventing the luteinizing hormone (LH) surge required for egg release.
Desogestrel-Ethinyl Estradiol 28 tablets · The Hospital for Sick Children · Contraception / Gynecology
Desogestrel-ethinyl estradiol is a combined oral contraceptive that prevents ovulation by suppressing gonadotropin hormones and thickening cervical mucus.
LNG-EE · Organon and Co · Contraception / Gynecology
LNG-EE is a combined oral contraceptive containing levonorgestrel (a progestin) and ethinyl estradiol (an estrogen) that prevents pregnancy by suppressing ovulation and altering cervical mucus.