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ETHINYL ESTRADIOL AND LEVOGESTREL

FHI 360 · FDA-approved active Small molecule

ETHINYL ESTRADIOL AND LEVOGESTREL is a Combined oral contraceptive Small molecule drug developed by FHI 360. It is currently FDA-approved for Contraception / prevention of pregnancy.

This combination oral contraceptive prevents pregnancy by suppressing ovulation through hormonal inhibition of the hypothalamic-pituitary-ovarian axis.

This combination oral contraceptive prevents pregnancy by suppressing ovulation through hormonal inhibition of the hypothalamic-pituitary-ovarian axis. Used for Contraception / prevention of pregnancy.

At a glance

Generic nameETHINYL ESTRADIOL AND LEVOGESTREL
SponsorFHI 360
Drug classCombined oral contraceptive
TargetEstrogen receptor and progesterone receptor
ModalitySmall molecule
Therapeutic areaContraception / Reproductive Health
PhaseFDA-approved

Mechanism of action

Ethinyl estradiol (a synthetic estrogen) and levonorgestrel (a synthetic progestin) work synergistically to inhibit the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), preventing ovulation. The progestin component also thickens cervical mucus to impede sperm penetration and alters the endometrium to reduce implantation likelihood.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

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Frequently asked questions about ETHINYL ESTRADIOL AND LEVOGESTREL

What is ETHINYL ESTRADIOL AND LEVOGESTREL?

ETHINYL ESTRADIOL AND LEVOGESTREL is a Combined oral contraceptive drug developed by FHI 360, indicated for Contraception / prevention of pregnancy.

How does ETHINYL ESTRADIOL AND LEVOGESTREL work?

This combination oral contraceptive prevents pregnancy by suppressing ovulation through hormonal inhibition of the hypothalamic-pituitary-ovarian axis.

What is ETHINYL ESTRADIOL AND LEVOGESTREL used for?

ETHINYL ESTRADIOL AND LEVOGESTREL is indicated for Contraception / prevention of pregnancy.

Who makes ETHINYL ESTRADIOL AND LEVOGESTREL?

ETHINYL ESTRADIOL AND LEVOGESTREL is developed and marketed by FHI 360 (see full FHI 360 pipeline at /company/fhi-360).

What drug class is ETHINYL ESTRADIOL AND LEVOGESTREL in?

ETHINYL ESTRADIOL AND LEVOGESTREL belongs to the Combined oral contraceptive class. See all Combined oral contraceptive drugs at /class/combined-oral-contraceptive.

What development phase is ETHINYL ESTRADIOL AND LEVOGESTREL in?

ETHINYL ESTRADIOL AND LEVOGESTREL is FDA-approved (marketed).

What are the side effects of ETHINYL ESTRADIOL AND LEVOGESTREL?

Common side effects of ETHINYL ESTRADIOL AND LEVOGESTREL include Nausea, Headache, Breast tenderness, Breakthrough bleeding, Mood changes, Venous thromboembolism.

What does ETHINYL ESTRADIOL AND LEVOGESTREL target?

ETHINYL ESTRADIOL AND LEVOGESTREL targets Estrogen receptor and progesterone receptor and is a Combined oral contraceptive.

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