Central Nervous System Stimulant

This page covers all Central Nervous System Stimulant drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Sodium-dependent dopamine transporter, Dopamine transporter (DAT) and norepinephrine transporter (NET), Dopamine transporter (DAT), Norepinephrine transporter (NET).

Targets

Sodium-dependent dopamine transporter · Dopamine transporter (DAT) and norepinephrine transporter (NET) · Dopamine transporter (DAT), Norepinephrine transporter (NET) · Dopamine transporter · Adenosine receptor · Norepinephrine transporter

Marketed (9)

• Vyvanse · Takeda · Metabolic · 3200
  Vyvanse works by blocking the dopamine transporter, allowing more dopamine to be available in the brain.
• Amphetamine Sulfate · Azurity · Metabolic · 172.0
• Amphetamine Sulfate · UCB · Metabolic · 172.0
• TED · Shire · Neurology / Psychiatry
  TED is a prodrug that is converted to active metabolites to treat attention-deficit/hyperactivity disorder (ADHD) by enhancing central nervous system stimulation.
• Methylphenidate Hydrochloride Controlled-Release Capsules · McMaster University · Neurology/Psychiatry
  Methylphenidate is a central nervous system stimulant that increases dopamine and norepinephrine activity in the brain by blocking their reuptake at the presynaptic neuron.
• Osmotic-release oral system methylphenidate · Eli Lilly and Company · Neurology / Psychiatry
  Methylphenidate is a central nervous system stimulant that increases dopamine and norepinephrine activity in the brain by blocking their reuptake at the synapse.
• Focalin XR · Novartis · Psychiatry / Neurology
  Focalin XR is an extended-release formulation of dexmethylphenidate that increases dopamine and norepinephrine activity in the brain by blocking their reuptake at the presynaptic neuron.
• DEXTROAMPHETAMINE · Metabolic
• Focalin · Novartis · Neuroscience
  Focalin works by blocking the dopamine transporter, allowing more dopamine to be available in the brain.

Phase 3 pipeline (10)

• Methylphenidate, non-retard · Wuerzburg University Hospital · Neurology
  Methylphenidate is a central nervous system stimulant that works by increasing the levels of dopamine and norepinephrine in the brain.
• Stimus (NNG-DEPO) · Nanogen Pharmaceutical Biotechnology Joint Stock Company · Neurology
  Stimus (NNG-DEPO) is a stimulant medication that works by increasing the levels of certain neurotransmitters in the brain.
• methylphenidate hydrochloride extended-release tablets · McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. · Attention deficit hyperactivity disorder (ADHD)
  Methylphenidate hydrochloride is a central nervous system stimulant that works by increasing the levels of dopamine and norepinephrine in the brain.
• Roxane Laboratories Inc., USA · Thinq Pharma-CRO Pte. Ltd. · Attention deficit hyperactivity disorder
  Roxane Laboratories Inc., USA's drug is a central nervous system stimulant.
• open label PR OROS methylphenidate · Janssen-Cilag International NV · Attention deficit hyperactivity disorder
  Methylphenidate is a central nervous system stimulant that works by increasing the levels of dopamine and norepinephrine in the brain.
• Usual treatment for ADHD · Puerta de Hierro University Hospital · Neurology
  Stimulates the brain to increase focus and attention by increasing the levels of certain neurotransmitters.
• Ritalin (methylphenidate) · Alza Corporation, DE, USA · Attention deficit hyperactivity disorder (ADHD)
  Ritalin (methylphenidate) works by increasing the levels of dopamine and norepinephrine in the brain, which helps to improve attention and reduce impulsivity.
• double blind PR OROS methylphenidate · Janssen-Cilag International NV · Central Nervous System
  Methylphenidate is a central nervous system stimulant that works by increasing the levels of dopamine and norepinephrine in the brain.
• GAMALINE® · Phytopharm Consulting Brazil · Psychiatry
  GAMALINE is a medication used to treat attention deficit hyperactivity disorder (ADHD).
• citrate of caffeine · Assistance Publique Hopitaux De Marseille · Neurology
  Caffeine citrate acts as a central nervous system stimulant by inhibiting adenosine receptors.

Phase 2 pipeline (6)

• Concerta AG formulation · Janssen Research & Development, LLC · Neurology
  Methylphenidate acts as a norepinephrine-dopamine reuptake inhibitor.
• IV doxapram · Alexza Pharmaceuticals, Inc. · Respiratory
  Stimulates the central nervous system to increase respiratory rate
• CD-LD IR · Impax Laboratories, LLC · Psychiatry
  CD-LD IR is a central nervous system stimulant used to treat attention deficit hyperactivity disorder (ADHD).
• Concerta EG formulation · Janssen Research & Development, LLC · Neurology
  Methylphenidate acts as a norepinephrine-dopamine reuptake inhibitor.
• DEX IR tablets · Prof. Dr. Frank Behrens · Attention deficit hyperactivity disorder (ADHD), Narcolepsy
  DEX IR tablets are a type of dextroamphetamine, a central nervous system stimulant that works by increasing the levels of certain neurotransmitters in the brain.
• CD-LD CR · Impax Laboratories, LLC · Attention Deficit Hyperactivity Disorder (ADHD)
  CD-LD CR is a controlled-release formulation of a central nervous system stimulant.