Last reviewed · How we verify

Concerta AG formulation

Janssen Research & Development, LLC · Phase 2 active Small molecule

Methylphenidate acts as a norepinephrine-dopamine reuptake inhibitor.

Methylphenidate acts as a norepinephrine-dopamine reuptake inhibitor. Used for Attention Deficit Hyperactivity Disorder (ADHD).

At a glance

Generic nameConcerta AG formulation
Also known asMethylphenidate
SponsorJanssen Research & Development, LLC
Drug classCentral Nervous System Stimulant
TargetNorepinephrine transporter
ModalitySmall molecule
Therapeutic areaNeurology
PhasePhase 2

Mechanism of action

Methylphenidate increases the levels of norepinephrine and dopamine in the brain by preventing their reuptake, which improves attention and impulse control.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results