What are anthracycline drugs?

anthracycline drugs are pharmacologic agents that share a common mechanism (typically targeting DNA). 0 are currently marketed, with 3 more in clinical development.

anthracycline

0 marketed 3 in Phase 3

This page covers all anthracycline drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting DNA, topoisomerase II.

Targets

DNA · topoisomerase II

Phase 3 pipeline (3)

pixantrone, cyclophosphamide, vincristine, rituximab, prednisone · CTI BioPharma · Oncology
Pixantrone is a synthetic anthracenedione that intercalates DNA, thereby inhibiting DNA replication and transcription.
stealth liposomal doxorubicin · National Cancer Institute, Naples · Oncology
Stealth liposomal doxorubicin is a formulation of doxorubicin that uses liposomes to improve its delivery and reduce its cardiotoxicity.
non-pegylated liposomal doxorubicin · GBG Forschungs GmbH · Oncology
Non-pegylated liposomal doxorubicin is a chemotherapy medication that works by intercalating DNA strands, thereby inhibiting the progression of the enzyme topoisomerase II and inducing apoptosis in cancer cells.