Anesthetic combination

This page covers all Anesthetic combination drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting NMDA receptor (ketamine); GABA-A receptor (propofol).

Targets

NMDA receptor (ketamine); GABA-A receptor (propofol)

Marketed (3)

• Ketamina-Propofol Combination · Universidad de Cartagena · Anesthesiology
  A combination of ketamine (NMDA receptor antagonist) and propofol (GABA-A agonist) that produces rapid anesthesia and sedation through dual CNS depression pathways.
• Ketofol 1:3 ratio · Kasr El Aini Hospital · Anesthesia
  Ketofol is a fixed-ratio combination of ketamine and propofol that produces rapid sedation and anesthesia through dual action on NMDA receptors and GABA-A receptors.
• Ketamine with propofol · Henry M. Jackson Foundation for the Advancement of Military Medicine · Anesthesiology
  Ketamine and propofol together provide rapid-onset anesthesia and analgesia by blocking NMDA receptors and enhancing GABAergic inhibition, respectively.