Who are Topical, intra-oral ketoprofen gel's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Standard Dose Ibuprofen, Codeine paracetamol, Pranoprofen eye drops, optimized ibuprofen, Ibuprofen, Hydrocortisone, naproxen sodium codein.

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Last reviewed 2026-05-18 · How we verify

Topical, intra-oral ketoprofen gel — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Topical, intra-oral ketoprofen gel (Topical, intra-oral ketoprofen gel) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NSAID. Area: Pain management.

phase 3 NSAID COX-1, COX-2 Pain management Small molecule Live · refreshed every 30 min

Target snapshot

Topical, intra-oral ketoprofen gel (Topical, intra-oral ketoprofen gel) — Behar, Caren, M.D.. Ketoprofen works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins, leading to reduced inflammation and pain.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Topical, intra-oral ketoprofen gel TARGET	Topical, intra-oral ketoprofen gel	Behar, Caren, M.D.	phase 3	NSAID	COX-1, COX-2
Standard Dose Ibuprofen	Standard Dose Ibuprofen	Ottawa Hospital Research Institute	marketed	Nonsteroidal anti-inflammatory drug (NSAID)	COX-1, COX-2
Codeine paracetamol	Codeine paracetamol	Napp Pharmaceuticals Limited	marketed	Opioid analgesic combination	Opioid receptors (μ, δ, κ); cyclooxygenase (COX-1, COX-2)
Pranoprofen eye drops	Pranoprofen eye drops	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine	marketed	Nonsteroidal anti-inflammatory drug (NSAID)	Cyclooxygenase (COX-1, COX-2)
optimized ibuprofen	optimized ibuprofen	OSF Healthcare System	marketed	Nonsteroidal anti-inflammatory drug (NSAID)	COX-1, COX-2
Ibuprofen, Hydrocortisone	Ibuprofen, Hydrocortisone	X-pert Med GmbH	marketed	NSAID + corticosteroid combination	COX-1, COX-2, glucocorticoid receptor
naproxen sodium codein	naproxen sodium codein	Diskapi Yildirim Beyazit Education and Research Hospital	marketed	NSAID + opioid combination analgesic	COX-1, COX-2, mu opioid receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

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Cite this brief

Drug Landscape (2026). Topical, intra-oral ketoprofen gel — Competitive Intelligence Brief. https://druglandscape.com/ci/topical-intra-oral-ketoprofen-gel. Accessed 2026-05-18.

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