Topical 2,5% lidocaine + 2,5% prilocaine gel — Competitive Intelligence Brief

Topical 2,5% lidocaine + 2,5% prilocaine gel (Topical 2,5% lidocaine + 2,5% prilocaine gel) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Pain management.

phase 3 Local anesthetic Voltage-gated sodium channels Pain management Small molecule

Target snapshot

Topical 2,5% lidocaine + 2,5% prilocaine gel (Topical 2,5% lidocaine + 2,5% prilocaine gel) — Pontificia Universidad Catolica de Chile. Lidocaine and prilocaine work by blocking the action of sodium channels in nerve cells, preventing the transmission of pain signals.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Topical 2,5% lidocaine + 2,5% prilocaine gel TARGET	Topical 2,5% lidocaine + 2,5% prilocaine gel	Pontificia Universidad Catolica de Chile	phase 3	Local anesthetic	Voltage-gated sodium channels
Lidocaine solution ("A")	Lidocaine solution ("A")	Hospital Universitari de Bellvitge	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine gel 2%	Lidocaine gel 2%	Atlantic Health System	marketed	Local anesthetic	Voltage-gated sodium channels
lidocaine infusion	lidocaine infusion	Medical University of Warsaw	marketed	Local anesthetic / Sodium channel blocker	Voltage-gated sodium channels
Ropivacaine 0.2% for LFCB	Ropivacaine 0.2% for LFCB	Poznan University of Medical Sciences	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Lidocaine/tetracaine patch	Lidocaine/tetracaine patch	East Carolina University	marketed	Local anesthetic combination	Voltage-gated sodium channels
Lidocaine (drug)	Lidocaine (drug)	Daniel A Tonetti, MD	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class