SUPREP Bowel Prep Kit — Competitive Intelligence Brief

SUPREP Bowel Prep Kit (SUPREP Bowel Prep Kit) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Osmotic laxative. Area: Metabolic.

marketed Osmotic laxative Intestinal lumen Metabolic Small molecule

Target snapshot

SUPREP Bowel Prep Kit (SUPREP Bowel Prep Kit) — Braintree Laboratories. SUPREP works by drawing water into the intestines to flush out the contents, preparing the bowel for colonoscopy.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
SUPREP Bowel Prep Kit TARGET	SUPREP Bowel Prep Kit	Braintree Laboratories	marketed	Osmotic laxative	Intestinal lumen
Standard full-volume PEG	Standard full-volume PEG	Kyunghee University Medical Center	marketed	Osmotic laxative	Intestinal lumen
sodium zirconium cyclic silicate	sodium zirconium cyclic silicate	Peking University First Hospital	marketed	Potassium binder	Potassium ion (K+) in gastrointestinal lumen
Patiromer Oral Product	Patiromer Oral Product	Wake Forest University Health Sciences	marketed	Potassium binder	Potassium ion (K+) in gastrointestinal lumen
Lokelma Oral Product	Lokelma Oral Product	St George's, University of London	phase 3	Potassium binder	Potassium ion (K+) in gastrointestinal lumen
Pizensy	LACTITOL	Braintree Labs	marketed	Osmotic Laxative		2020-01-01
Miralax	Macrogol	Braintree	marketed	Osmotic Laxative [EPC]		1984-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

• 2032-03-09 — Miralax · 10780112 · US
• 2032-03-09 — Miralax · 11529368 · US
• 2032-03-09 — Miralax · 10792306 · US
• 2032-03-25 — Miralax · 10646512 · US
• 2032-08-11 — Miralax · 9592252 · US
• 2033-09-10 — Miralax · 9326969 · US
• 2033-09-10 — Miralax · 9707297 · US
• 2033-09-10 — Miralax · 8999313 · US
• 2033-09-10 — Miralax · 10918723 · US
• 2033-09-10 — Miralax · 10016504 · US

Sponsor landscape (Osmotic laxative class)

1. Brooke Army Medical Center · 2 drugs in this class
2. Cleveland Clinic Florida · 2 drugs in this class
3. Gastroenterology Services, Ltd. · 2 drugs in this class
4. Ipsen · 2 drugs in this class
5. Benaroya Research Institute · 1 drug in this class
6. Bo-In Lee · 1 drug in this class
7. Amsterdam UMC, location VUmc · 1 drug in this class
8. C.B. Fleet Company, Inc. · 1 drug in this class
9. Bayer · 1 drug in this class
10. Braintree Laboratories · 1 drug in this class