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Patiromer Oral Product

Wake Forest University Health Sciences · FDA-approved active Small molecule

Patiromer is a non-absorbed potassium binder that sequesters potassium in the gastrointestinal tract to reduce serum potassium levels.

Patiromer is a non-absorbed potassium binder that exchanges sodium for potassium in the gastrointestinal tract, reducing serum potassium levels. Used for Hyperkalemia (elevated serum potassium levels).

At a glance

Generic namePatiromer Oral Product
Also known asValtressa
SponsorWake Forest University Health Sciences
Drug classPotassium binder
TargetPotassium ion (K+) in gastrointestinal lumen
ModalitySmall molecule
Therapeutic areaCardiovascular
PhaseFDA-approved

Mechanism of action

Patiromer is a cation exchange polymer that binds potassium ions in the colon through ionic interactions, preventing potassium reabsorption and increasing fecal potassium excretion. This mechanism allows for reduction of hyperkalemia without systemic absorption, making it suitable for chronic management of elevated serum potassium levels in patients taking medications that increase potassium retention.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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