Last reviewed · How we verify
SUPREP Bowel Prep Kit
SUPREP works by drawing water into the intestines to flush out the contents, preparing the bowel for colonoscopy.
SUPREP Bowel Prep Kit is a prescription medication used for bowel cleansing before colonoscopy. It is manufactured by Braintree Laboratories and does not have an FDA label. The kit contains polyethylene glycol 3350, sodium sulfate, sodium chloride, and potassium chloride. Common side effects include nausea, vomiting, abdominal distension, and headache. SUPREP is generally well-tolerated but has specific contraindications and warnings. It competes in the bowel preparation market with other products like MoviPrep and Golytely.
At a glance
| Generic name | SUPREP Bowel Prep Kit |
|---|---|
| Sponsor | Braintree Laboratories |
| Drug class | Osmotic laxative |
| Target | Intestinal lumen |
| Modality | Small molecule |
| Therapeutic area | Metabolic |
| Phase | FDA-approved |
Mechanism of action
The osmotic laxative properties of polyethylene glycol 3350 and the electrolytes in SUPREP draw water into the intestines, causing a large volume of fluid to move through the colon and cleanse it.
Approved indications
Common side effects
- Nausea
- Vomiting
- Abdominal distension
- Headache
Key clinical trials
- Pilot Study to Assess Tolerability and Feasibility of Oral Sulfate Solution (SUPREP) in Hospitalized Patients (NA)
- Efficacy and Tolerability of Suprep With and Without Simethicone for Routine Colonoscopy for Colorectal Cancer Screening (NA)
- BLI800-480: A Safety and Efficacy Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects (PHASE4)
Patents
| Patent | Expiry | Type |
|---|---|---|
| US7820198B2 |
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
| FDA Orange Book | Patents + exclusivity |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- SUPREP Bowel Prep Kit CI brief — competitive landscape report
- SUPREP Bowel Prep Kit updates RSS · CI watch RSS
- Braintree Laboratories portfolio CI