Sevoflurane or Propofol — Competitive Intelligence Brief

Sevoflurane or Propofol (Sevoflurane or Propofol) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: General anesthetic. Area: Anesthesiology.

marketed General anesthetic GABA-A receptor, NMDA glutamate receptor Anesthesiology Small molecule

Target snapshot

Sevoflurane or Propofol (Sevoflurane or Propofol) — University Health Network, Toronto. Sevoflurane and Propofol are general anesthetics that enhance inhibitory GABAergic neurotransmission and suppress excitatory glutamatergic signaling in the central nervous system to produce unconsciousness.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Sevoflurane or Propofol TARGET	Sevoflurane or Propofol	University Health Network, Toronto	marketed	General anesthetic	GABA-A receptor, NMDA glutamate receptor
Sevoflurane inhalant product	Sevoflurane inhalant product	Sunnybrook Health Sciences Centre	marketed	Volatile inhalational anesthetic	GABA-A receptor, NMDA glutamate receptor
Sevorane (sevoflurane, Abbott)	Sevorane (sevoflurane, Abbott)	Medical University of Gdansk	marketed	Volatile anesthetic	GABA-A receptor, NMDA glutamate receptor
General sevoflurane anaesthesia	General sevoflurane anaesthesia	KK Women's and Children's Hospital	phase 3	Volatile anesthetic agent	GABA-A receptor, NMDA glutamate receptor
Inhaled sedation with sevoflurane	Inhaled sedation with sevoflurane	University Hospital, Clermont-Ferrand	phase 3	Volatile anesthetic	GABA-A receptor, NMDA glutamate receptor
SEVOFLURANE	SEVOFLURANE		marketed	General Anesthetic [EPC]		1995-01-01
Suprane	DESFLURANE	Baxter	marketed	General Anesthetic [EPC]	GABA-A receptor; anion channel	1992-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (General anesthetic class)

1. Assistance Publique - Hôpitaux de Paris · 1 drug in this class
2. Chung-Ang University Gwangmyeong Hospital · 1 drug in this class
3. Fresenius Kabi · 1 drug in this class
4. Gangnam Severance Hospital · 1 drug in this class
5. Rigshospitalet, Denmark · 1 drug in this class
6. Seoul National University Hospital · 1 drug in this class
7. Universidade Estadual Paulista Júlio de Mesquita Filho · 1 drug in this class
8. University Health Network, Toronto · 1 drug in this class
9. Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · 1 drug in this class