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Plain bupivacaine — Competitive Intelligence Brief

Plain bupivacaine (Plain bupivacaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia Small molecule Live · refreshed every 30 min

Target snapshot

Plain bupivacaine (Plain bupivacaine) — Fayoum University Hospital. Bupivacaine blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials to produce local anesthesia.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Plain bupivacaine TARGET Plain bupivacaine Fayoum University Hospital marketed Local anesthetic Voltage-gated sodium channels
Levobupivacaine 0.5% + epinephrin 1/200000 Levobupivacaine 0.5% + epinephrin 1/200000 University Hospital, Antwerp marketed Local anesthetic with vasoconstrictor Voltage-gated sodium channels; alpha-adrenergic receptors
SUP Lidocaine SUP Lidocaine University of Michigan marketed Local anesthetic Voltage-gated sodium channels
Anesthetic Topical Adhesive Synera Anesthetic Topical Adhesive Synera Brown, Theodore R., M.D., MPH marketed Topical local anesthetic Voltage-gated sodium channels
Transdermal Lidocaine Patch Transdermal Lidocaine Patch University of Wisconsin, Madison marketed Local anesthetic Voltage-gated sodium channels
Topiramate monotherapy Topiramate monotherapy Johnson & Johnson Taiwan Ltd marketed Anticonvulsant / Antiepileptic agent GABA-A receptor; voltage-gated sodium channels
Ropivacaine 0,75% in PENG block Ropivacaine 0,75% in PENG block University of Liege marketed Local anesthetic (amide) Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

  1. University of California, San Diego · 3 drugs in this class
  2. Durect · 3 drugs in this class
  3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
  4. Wake Forest University Health Sciences · 3 drugs in this class
  5. Medical University of Vienna · 3 drugs in this class
  6. Imperial College London · 2 drugs in this class
  7. Hvidovre University Hospital · 2 drugs in this class
  8. Innocoll · 2 drugs in this class
  9. George Washington University · 2 drugs in this class
  10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). Plain bupivacaine — Competitive Intelligence Brief. https://druglandscape.com/ci/plain-bupivacaine. Accessed 2026-05-16.

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